LARP7 family proteins have conserved function in telomerase assembly

The telomerase holoenzyme is minimally composed of the reverse transcriptase and the RNA template. Here the authors identify Lar7 as a member of the full complex that helps to stabilise it and protect telomerase RNA from degradation.

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Autores principales:	Laura C. Collopy, Tracy L. Ware, Tomas Goncalves, Sunnvør í Kongsstovu, Qian Yang, Hanna Amelina, Corinne Pinder, Ala Alenazi, Vera Moiseeva, Siân R. Pearson, Christine A. Armstrong, Kazunori Tomita
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2f530556f00745c9b6030e3daa173ab6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:2f530556f00745c9b6030e3daa173ab62021-12-02T16:50:09ZLARP7 family proteins have conserved function in telomerase assembly10.1038/s41467-017-02296-42041-1723https://doaj.org/article/2f530556f00745c9b6030e3daa173ab62018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02296-4https://doaj.org/toc/2041-1723The telomerase holoenzyme is minimally composed of the reverse transcriptase and the RNA template. Here the authors identify Lar7 as a member of the full complex that helps to stabilise it and protect telomerase RNA from degradation.Laura C. CollopyTracy L. WareTomas GoncalvesSunnvør í KongsstovuQian YangHanna AmelinaCorinne PinderAla AlenaziVera MoiseevaSiân R. PearsonChristine A. ArmstrongKazunori TomitaNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Laura C. Collopy Tracy L. Ware Tomas Goncalves Sunnvør í Kongsstovu Qian Yang Hanna Amelina Corinne Pinder Ala Alenazi Vera Moiseeva Siân R. Pearson Christine A. Armstrong Kazunori Tomita LARP7 family proteins have conserved function in telomerase assembly
description	The telomerase holoenzyme is minimally composed of the reverse transcriptase and the RNA template. Here the authors identify Lar7 as a member of the full complex that helps to stabilise it and protect telomerase RNA from degradation.
format	article
author	Laura C. Collopy Tracy L. Ware Tomas Goncalves Sunnvør í Kongsstovu Qian Yang Hanna Amelina Corinne Pinder Ala Alenazi Vera Moiseeva Siân R. Pearson Christine A. Armstrong Kazunori Tomita
author_facet	Laura C. Collopy Tracy L. Ware Tomas Goncalves Sunnvør í Kongsstovu Qian Yang Hanna Amelina Corinne Pinder Ala Alenazi Vera Moiseeva Siân R. Pearson Christine A. Armstrong Kazunori Tomita
author_sort	Laura C. Collopy
title	LARP7 family proteins have conserved function in telomerase assembly
title_short	LARP7 family proteins have conserved function in telomerase assembly
title_full	LARP7 family proteins have conserved function in telomerase assembly
title_fullStr	LARP7 family proteins have conserved function in telomerase assembly
title_full_unstemmed	LARP7 family proteins have conserved function in telomerase assembly
title_sort	larp7 family proteins have conserved function in telomerase assembly
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/2f530556f00745c9b6030e3daa173ab6
work_keys_str_mv	AT lauraccollopy larp7familyproteinshaveconservedfunctionintelomeraseassembly AT tracylware larp7familyproteinshaveconservedfunctionintelomeraseassembly AT tomasgoncalves larp7familyproteinshaveconservedfunctionintelomeraseassembly AT sunnvørikongsstovu larp7familyproteinshaveconservedfunctionintelomeraseassembly AT qianyang larp7familyproteinshaveconservedfunctionintelomeraseassembly AT hannaamelina larp7familyproteinshaveconservedfunctionintelomeraseassembly AT corinnepinder larp7familyproteinshaveconservedfunctionintelomeraseassembly AT alaalenazi larp7familyproteinshaveconservedfunctionintelomeraseassembly AT veramoiseeva larp7familyproteinshaveconservedfunctionintelomeraseassembly AT sianrpearson larp7familyproteinshaveconservedfunctionintelomeraseassembly AT christineaarmstrong larp7familyproteinshaveconservedfunctionintelomeraseassembly AT kazunoritomita larp7familyproteinshaveconservedfunctionintelomeraseassembly
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LARP7 family proteins have conserved function in telomerase assembly

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