Mapping the serum proteome to neurological diseases using whole genome sequencing

Serum proteins are easily accessible biomarkers and drug targets. Here, the authors use whole genome sequencing data to describe the genetic architecture of neurologically-relevant serum proteins and establish causal protein-neurological disease relationships.

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Autores principales:	Grace Png, Andrei Barysenka, Linda Repetto, Pau Navarro, Xia Shen, Maik Pietzner, Eleanor Wheeler, Nicholas J. Wareham, Claudia Langenberg, Emmanouil Tsafantakis, Maria Karaleftheri, George Dedoussis, Anders Mälarstig, James F. Wilson, Arthur Gilly, Eleftheria Zeggini
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2f5b2a2d19854a24b3c3f873cde81d0b
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spelling	oai:doaj.org-article:2f5b2a2d19854a24b3c3f873cde81d0b2021-12-05T12:22:15ZMapping the serum proteome to neurological diseases using whole genome sequencing10.1038/s41467-021-27387-12041-1723https://doaj.org/article/2f5b2a2d19854a24b3c3f873cde81d0b2021-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-27387-1https://doaj.org/toc/2041-1723Serum proteins are easily accessible biomarkers and drug targets. Here, the authors use whole genome sequencing data to describe the genetic architecture of neurologically-relevant serum proteins and establish causal protein-neurological disease relationships.Grace PngAndrei BarysenkaLinda RepettoPau NavarroXia ShenMaik PietznerEleanor WheelerNicholas J. WarehamClaudia LangenbergEmmanouil TsafantakisMaria KaraleftheriGeorge DedoussisAnders MälarstigJames F. WilsonArthur GillyEleftheria ZegginiNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Grace Png Andrei Barysenka Linda Repetto Pau Navarro Xia Shen Maik Pietzner Eleanor Wheeler Nicholas J. Wareham Claudia Langenberg Emmanouil Tsafantakis Maria Karaleftheri George Dedoussis Anders Mälarstig James F. Wilson Arthur Gilly Eleftheria Zeggini Mapping the serum proteome to neurological diseases using whole genome sequencing
description	Serum proteins are easily accessible biomarkers and drug targets. Here, the authors use whole genome sequencing data to describe the genetic architecture of neurologically-relevant serum proteins and establish causal protein-neurological disease relationships.
format	article
author	Grace Png Andrei Barysenka Linda Repetto Pau Navarro Xia Shen Maik Pietzner Eleanor Wheeler Nicholas J. Wareham Claudia Langenberg Emmanouil Tsafantakis Maria Karaleftheri George Dedoussis Anders Mälarstig James F. Wilson Arthur Gilly Eleftheria Zeggini
author_facet	Grace Png Andrei Barysenka Linda Repetto Pau Navarro Xia Shen Maik Pietzner Eleanor Wheeler Nicholas J. Wareham Claudia Langenberg Emmanouil Tsafantakis Maria Karaleftheri George Dedoussis Anders Mälarstig James F. Wilson Arthur Gilly Eleftheria Zeggini
author_sort	Grace Png
title	Mapping the serum proteome to neurological diseases using whole genome sequencing
title_short	Mapping the serum proteome to neurological diseases using whole genome sequencing
title_full	Mapping the serum proteome to neurological diseases using whole genome sequencing
title_fullStr	Mapping the serum proteome to neurological diseases using whole genome sequencing
title_full_unstemmed	Mapping the serum proteome to neurological diseases using whole genome sequencing
title_sort	mapping the serum proteome to neurological diseases using whole genome sequencing
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2f5b2a2d19854a24b3c3f873cde81d0b
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Mapping the serum proteome to neurological diseases using whole genome sequencing

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