Using the Microwell-mesh to culture microtissues in vitro and as a carrier to implant microtissues in vivo into mice

Abstract Prostate cancer (PCa) patient-derived xenografts (PDXs) are commonly propagated by serial transplantation of “pieces” of tumour in mice, but the cellular composition of pieces is not standardised. Herein, we optimised a microwell platform, the Microwell-mesh, to aggregate precise numbers of...

Full description

Saved in:
Bibliographic Details
Main Authors: Melissa E. Monterosso, Kathryn Futrega, William B. Lott, Ian Vela, Elizabeth D. Williams, Michael R. Doran
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/2f5eb33aec0547329c75ee64f3601dbc
Tags: Add Tag
No Tags, Be the first to tag this record!