RIG-I ATPase Activity and Discrimination of Self-RNA versus Non-Self-RNA
ABSTRACT Many RNA viruses are detected by retinoic acid-inducible gene i (RIG-I), a cytoplasmic sensor that triggers an antiviral response upon binding non-self-RNA that contains a stretch of double-stranded RNA (dsRNA) bearing a base-paired 5′ ppp nucleotide. To gain insight into how RIG-I discrimi...
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Autores principales: | Stéphanie Anchisi, Jessica Guerra, Dominique Garcin |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2015
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Materias: | |
Acceso en línea: | https://doaj.org/article/2f69c082248d4abcb7dc70907c768c63 |
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