RIG-I ATPase Activity and Discrimination of Self-RNA versus Non-Self-RNA

ABSTRACT Many RNA viruses are detected by retinoic acid-inducible gene i (RIG-I), a cytoplasmic sensor that triggers an antiviral response upon binding non-self-RNA that contains a stretch of double-stranded RNA (dsRNA) bearing a base-paired 5′ ppp nucleotide. To gain insight into how RIG-I discrimi...

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Autores principales: Stéphanie Anchisi, Jessica Guerra, Dominique Garcin
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
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Acceso en línea:https://doaj.org/article/2f69c082248d4abcb7dc70907c768c63
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