Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and Macrophages

Background and purpose: FXR is a promising target for the treatment of human cholestatic liver disease (CLD). SIRT1 is a deacetylase which promotes FXR activity through deacetylating FXR. Pterostilbene (PTE) is an activator of SIRT1. However, the role of PTE in cholestasis has so far not been invest...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Chuanrui Ma, Jiaqing Xiang, Guixiao Huang, Yaxi Zhao, Xinyu Wang, Han Wu, Kewei Jiang, Zhen Liang, Lin Kang, Guangyan Yang, Shu Yang
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
Materias:
FXR
p53
Acceso en línea:https://doaj.org/article/2f6b7998610b4b7dbe7599cf68119b5f
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares