HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma
Abstract Lung adenocarcinoma is one of the most frequent tumor subtypes, involving changes in a variety of oncogenes and tumor suppressor genes. Hydroxysteroid 17-Beta Dehydrogenase 6 (HSD17B6) could synthetize dihydrotestosterone, abnormal levels of which are associated with progression of multiple...
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Auteurs principaux: | Tian Tian, Fu Hong, Zhiwen Wang, Jiaru Hu, Ni Chen, Lei Lv, Qiyi Yi |
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Format: | article |
Langue: | EN |
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Nature Publishing Group
2021
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Accès en ligne: | https://doaj.org/article/2f71137f25e447fc9f77fe05a1dd4ff5 |
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