HSD17B6 downregulation predicts poor prognosis and drives tumor progression via activating Akt signaling pathway in lung adenocarcinoma

Abstract Lung adenocarcinoma is one of the most frequent tumor subtypes, involving changes in a variety of oncogenes and tumor suppressor genes. Hydroxysteroid 17-Beta Dehydrogenase 6 (HSD17B6) could synthetize dihydrotestosterone, abnormal levels of which are associated with progression of multiple...

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Bibliographic Details
Main Authors: Tian Tian, Fu Hong, Zhiwen Wang, Jiaru Hu, Ni Chen, Lei Lv, Qiyi Yi
Format: article
Language:EN
Published: Nature Publishing Group 2021
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Online Access:https://doaj.org/article/2f71137f25e447fc9f77fe05a1dd4ff5
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