Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases

Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases

Alcohol use disorder and drinks per week both have been studied genetically and have different correlations with psychiatric diseases. Here the authors integrate multi-omics data to identify unique and shared variants, genes and pathways for alcohol use disorder and drinks per week.

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Detalles Bibliográficos
Autores principales: Manav Kapoor, Michael J. Chao, Emma C. Johnson, Gloriia Novikova, Dongbing Lai, Jacquelyn L. Meyers, Jessica Schulman, John I. Nurnberger, Bernice Porjesz, Yunlong Liu, The Collaborative Study on the Genetics of Alcoholism (COGA), Tatiana Foroud, Howard J. Edenberg, Edoardo Marcora, Arpana Agrawal, Alison Goate
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/2f7874ae384e400ab64698142f8c1fce
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Descripción
Sumario:Alcohol use disorder and drinks per week both have been studied genetically and have different correlations with psychiatric diseases. Here the authors integrate multi-omics data to identify unique and shared variants, genes and pathways for alcohol use disorder and drinks per week.

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