Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases

Alcohol use disorder and drinks per week both have been studied genetically and have different correlations with psychiatric diseases. Here the authors integrate multi-omics data to identify unique and shared variants, genes and pathways for alcohol use disorder and drinks per week.

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Auteurs principaux:	Manav Kapoor, Michael J. Chao, Emma C. Johnson, Gloriia Novikova, Dongbing Lai, Jacquelyn L. Meyers, Jessica Schulman, John I. Nurnberger, Bernice Porjesz, Yunlong Liu, The Collaborative Study on the Genetics of Alcoholism (COGA), Tatiana Foroud, Howard J. Edenberg, Edoardo Marcora, Arpana Agrawal, Alison Goate
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2021
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/2f7874ae384e400ab64698142f8c1fce
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spelling	oai:doaj.org-article:2f7874ae384e400ab64698142f8c1fce2021-12-02T16:45:30ZMulti-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases10.1038/s41467-021-25392-y2041-1723https://doaj.org/article/2f7874ae384e400ab64698142f8c1fce2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25392-yhttps://doaj.org/toc/2041-1723Alcohol use disorder and drinks per week both have been studied genetically and have different correlations with psychiatric diseases. Here the authors integrate multi-omics data to identify unique and shared variants, genes and pathways for alcohol use disorder and drinks per week.Manav KapoorMichael J. ChaoEmma C. JohnsonGloriia NovikovaDongbing LaiJacquelyn L. MeyersJessica SchulmanJohn I. NurnbergerBernice PorjeszYunlong LiuThe Collaborative Study on the Genetics of Alcoholism (COGA)Tatiana ForoudHoward J. EdenbergEdoardo MarcoraArpana AgrawalAlison GoateNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Manav Kapoor Michael J. Chao Emma C. Johnson Gloriia Novikova Dongbing Lai Jacquelyn L. Meyers Jessica Schulman John I. Nurnberger Bernice Porjesz Yunlong Liu The Collaborative Study on the Genetics of Alcoholism (COGA) Tatiana Foroud Howard J. Edenberg Edoardo Marcora Arpana Agrawal Alison Goate Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases
description	Alcohol use disorder and drinks per week both have been studied genetically and have different correlations with psychiatric diseases. Here the authors integrate multi-omics data to identify unique and shared variants, genes and pathways for alcohol use disorder and drinks per week.
format	article
author	Manav Kapoor Michael J. Chao Emma C. Johnson Gloriia Novikova Dongbing Lai Jacquelyn L. Meyers Jessica Schulman John I. Nurnberger Bernice Porjesz Yunlong Liu The Collaborative Study on the Genetics of Alcoholism (COGA) Tatiana Foroud Howard J. Edenberg Edoardo Marcora Arpana Agrawal Alison Goate
author_facet	Manav Kapoor Michael J. Chao Emma C. Johnson Gloriia Novikova Dongbing Lai Jacquelyn L. Meyers Jessica Schulman John I. Nurnberger Bernice Porjesz Yunlong Liu The Collaborative Study on the Genetics of Alcoholism (COGA) Tatiana Foroud Howard J. Edenberg Edoardo Marcora Arpana Agrawal Alison Goate
author_sort	Manav Kapoor
title	Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases
title_short	Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases
title_full	Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases
title_fullStr	Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases
title_full_unstemmed	Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases
title_sort	multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2f7874ae384e400ab64698142f8c1fce
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Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases

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