Effect of computerized cognitive training with virtual spatial navigation task during bed rest immobilization and recovery on vascular function: A pilot study

Nandu Goswami,1 Voyko Kavcic,2 Uros Marusic,3 Bostjan Simunic,3 Andreas Rössler,1 Helmut Hinghofer-Szalkay,1 Rado Pisot3 1Institute of Physiology, Medical University of Graz, Graz, Austria; 2Institute of Gerontology, Wayne State University, Detroit, MI, USA; 3Institute for Kinesiology Rese...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Goswami N, Kavcic V, Marusic U, Simunic B, Rössler A, Hinghofer-Szalkay H, Pisot R
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2015
Materias:	Computerized Cognitive training Spatial navigation Bed rest EndoPAT® Vascular changes Aging Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/2f794b82714d43299e62aaa1ff7e0afc
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2f794b82714d43299e62aaa1ff7e0afc
record_format	dspace
spelling	oai:doaj.org-article:2f794b82714d43299e62aaa1ff7e0afc2021-12-02T03:14:34ZEffect of computerized cognitive training with virtual spatial navigation task during bed rest immobilization and recovery on vascular function: A pilot study1178-1998https://doaj.org/article/2f794b82714d43299e62aaa1ff7e0afc2015-02-01T00:00:00Zhttps://www.dovepress.com/effect-of-computerized-cognitive-training-with-virtual-spatial-navigat-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Nandu Goswami,1 Voyko Kavcic,2 Uros Marusic,3 Bostjan Simunic,3 Andreas Rössler,1 Helmut Hinghofer-Szalkay,1 Rado Pisot3 1Institute of Physiology, Medical University of Graz, Graz, Austria; 2Institute of Gerontology, Wayne State University, Detroit, MI, USA; 3Institute for Kinesiology Research, University of Primorska, Ankaran, Slovenia Abstract: We investigated the effects of bed rest (BR) immobilization, with and without computerized cognitive training with virtual spatial navigation task (CCT), on vascular endothelium on older subjects. The effects of 14-day BR immobilization in healthy older males (n=16) of ages 53–65 years on endothelial function were studied using EndoPAT®, a noninvasive and user-independent method. From the group of 16 older men, 8 randomly received CCT during the BR, using virtual navigation tasks in a virtual environment with joystick device. In all the cases, EndoPAT assessments were done at pre- and post-BR immobilization as well as following 28 days of ambulatory recovery. The EndoPAT index increased from 1.53±0.09 (mean ± standard error of the mean) at baseline to 1.61±0.16 following immobilization (P=0.62) in the group with CCT. The EndoPAT index decreased from 2.06±0.13 (mean ± standard error of the mean) at baseline to 1.70±0.09 at the last day of BR study, day 14 (BR14) (P=0.09) in the control group. Additionally, there were no statistically significant differences between BR14 and at 28 days of follow-up (rehabilitation program) (R28). Our results show a trend of immobilization in older persons affecting the vasoconstrictory endothelial response. As the control subjects had a greater increase in EndoPAT index after R28 (+0.018) compared to subjects who had cognitive training (+0.11) (calculated from the first day of BR study), it is possible that cognitive training during BR does not improve endothelial function but rather contributes to slowing down the impairment of endothelial function. Finally, our results also show that EndoPAT may be a useful noninvasive tool to assess the vascular reactivity. Keywords: computerized cognitive training, spatial navigation, bed rest, EndoPAT®, vascular changes, agingGoswami NKavcic VMarusic USimunic BRössler AHinghofer-Szalkay HPisot RDove Medical PressarticleComputerized Cognitive trainingSpatial navigationBed restEndoPAT®Vascular changesAgingGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 10, Pp 453-459 (2015)
institution	DOAJ
collection	DOAJ
language	EN
topic	Computerized Cognitive training Spatial navigation Bed rest EndoPAT® Vascular changes Aging Geriatrics RC952-954.6
spellingShingle	Computerized Cognitive training Spatial navigation Bed rest EndoPAT® Vascular changes Aging Geriatrics RC952-954.6 Goswami N Kavcic V Marusic U Simunic B Rössler A Hinghofer-Szalkay H Pisot R Effect of computerized cognitive training with virtual spatial navigation task during bed rest immobilization and recovery on vascular function: A pilot study
description	Nandu Goswami,1 Voyko Kavcic,2 Uros Marusic,3 Bostjan Simunic,3 Andreas Rössler,1 Helmut Hinghofer-Szalkay,1 Rado Pisot3 1Institute of Physiology, Medical University of Graz, Graz, Austria; 2Institute of Gerontology, Wayne State University, Detroit, MI, USA; 3Institute for Kinesiology Research, University of Primorska, Ankaran, Slovenia Abstract: We investigated the effects of bed rest (BR) immobilization, with and without computerized cognitive training with virtual spatial navigation task (CCT), on vascular endothelium on older subjects. The effects of 14-day BR immobilization in healthy older males (n=16) of ages 53–65 years on endothelial function were studied using EndoPAT®, a noninvasive and user-independent method. From the group of 16 older men, 8 randomly received CCT during the BR, using virtual navigation tasks in a virtual environment with joystick device. In all the cases, EndoPAT assessments were done at pre- and post-BR immobilization as well as following 28 days of ambulatory recovery. The EndoPAT index increased from 1.53±0.09 (mean ± standard error of the mean) at baseline to 1.61±0.16 following immobilization (P=0.62) in the group with CCT. The EndoPAT index decreased from 2.06±0.13 (mean ± standard error of the mean) at baseline to 1.70±0.09 at the last day of BR study, day 14 (BR14) (P=0.09) in the control group. Additionally, there were no statistically significant differences between BR14 and at 28 days of follow-up (rehabilitation program) (R28). Our results show a trend of immobilization in older persons affecting the vasoconstrictory endothelial response. As the control subjects had a greater increase in EndoPAT index after R28 (+0.018) compared to subjects who had cognitive training (+0.11) (calculated from the first day of BR study), it is possible that cognitive training during BR does not improve endothelial function but rather contributes to slowing down the impairment of endothelial function. Finally, our results also show that EndoPAT may be a useful noninvasive tool to assess the vascular reactivity. Keywords: computerized cognitive training, spatial navigation, bed rest, EndoPAT®, vascular changes, aging
format	article
author	Goswami N Kavcic V Marusic U Simunic B Rössler A Hinghofer-Szalkay H Pisot R
author_facet	Goswami N Kavcic V Marusic U Simunic B Rössler A Hinghofer-Szalkay H Pisot R
author_sort	Goswami N
title	Effect of computerized cognitive training with virtual spatial navigation task during bed rest immobilization and recovery on vascular function: A pilot study
title_short	Effect of computerized cognitive training with virtual spatial navigation task during bed rest immobilization and recovery on vascular function: A pilot study
title_full	Effect of computerized cognitive training with virtual spatial navigation task during bed rest immobilization and recovery on vascular function: A pilot study
title_fullStr	Effect of computerized cognitive training with virtual spatial navigation task during bed rest immobilization and recovery on vascular function: A pilot study
title_full_unstemmed	Effect of computerized cognitive training with virtual spatial navigation task during bed rest immobilization and recovery on vascular function: A pilot study
title_sort	effect of computerized cognitive training with virtual spatial navigation task during bed rest immobilization and recovery on vascular function: a pilot study
publisher	Dove Medical Press
publishDate	2015
url	https://doaj.org/article/2f794b82714d43299e62aaa1ff7e0afc
work_keys_str_mv	AT goswamin effectofcomputerizedcognitivetrainingwithvirtualspatialnavigationtaskduringbedrestimmobilizationandrecoveryonvascularfunctionapilotstudy AT kavcicv effectofcomputerizedcognitivetrainingwithvirtualspatialnavigationtaskduringbedrestimmobilizationandrecoveryonvascularfunctionapilotstudy AT marusicu effectofcomputerizedcognitivetrainingwithvirtualspatialnavigationtaskduringbedrestimmobilizationandrecoveryonvascularfunctionapilotstudy AT simunicb effectofcomputerizedcognitivetrainingwithvirtualspatialnavigationtaskduringbedrestimmobilizationandrecoveryonvascularfunctionapilotstudy AT roumlsslera effectofcomputerizedcognitivetrainingwithvirtualspatialnavigationtaskduringbedrestimmobilizationandrecoveryonvascularfunctionapilotstudy AT hinghoferszalkayh effectofcomputerizedcognitivetrainingwithvirtualspatialnavigationtaskduringbedrestimmobilizationandrecoveryonvascularfunctionapilotstudy AT pisotr effectofcomputerizedcognitivetrainingwithvirtualspatialnavigationtaskduringbedrestimmobilizationandrecoveryonvascularfunctionapilotstudy
_version_	1718401843771473920

Effect of computerized cognitive training with virtual spatial navigation task during bed rest immobilization and recovery on vascular function: A pilot study

Ejemplares similares