Posterior vitreous detachment and paravascular retinoschisis in highly myopic young patients detected by ultra-widefield OCT

Abstract The purpose of this study was to determine the relationship between a posterior vitreous detachment (PVD) and retinoschisis (RS) in 73 highly myopic (HM) young patients age 16.4 ± 6.9 years and 24 non-HM children age 8.4 ± 1.5 years. The presence of the paravascular retinal abnormalities wa...

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Autores principales:	Hiroyuki Takahashi, Noriko Nakao, Kosei Shinohara, Keigo Sugisawa, Kengo Uramoto, Tae Igarashi-Yokoi, Takeshi Yoshida, Kyoko Ohno-Matsui
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/2f97b309f5ca4fe9845a335066cd0db9
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spelling	oai:doaj.org-article:2f97b309f5ca4fe9845a335066cd0db92021-12-02T16:38:49ZPosterior vitreous detachment and paravascular retinoschisis in highly myopic young patients detected by ultra-widefield OCT10.1038/s41598-021-96783-w2045-2322https://doaj.org/article/2f97b309f5ca4fe9845a335066cd0db92021-08-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-96783-whttps://doaj.org/toc/2045-2322Abstract The purpose of this study was to determine the relationship between a posterior vitreous detachment (PVD) and retinoschisis (RS) in 73 highly myopic (HM) young patients age 16.4 ± 6.9 years and 24 non-HM children age 8.4 ± 1.5 years. The presence of the paravascular retinal abnormalities was determined in the images obtained by a ultra-widefield OCT (UWF OCT) instrument with an image field of 23 × 20 mm. The results showed that a partial PVD was detected in 15 (21%) of the HM patients, and the number increased significantly with increasing age (P = 0.02). PVDs of any type were not found in the non-HM eyes. The number of microvascular folds also increased with age in the HM patients (P = 0.03). Medium-reflective columnar tissues were present between the detached vitreous and inner retinal surface in 4 (5%) eyes of the HM patients. Myopic RS was found in 3 (4%) HM patients in the paravascular area but not in the macular area. These results suggest that early partial PVD may play a role in pathological and proliferative vitreous changes of HM eyes. An intense vitreoretinal traction with bridging tissues may cause the various paravascular retinal abnormalities. In HM eyes, paravascular RS is already present at an early age which may progress to macular RS with aging.Hiroyuki TakahashiNoriko NakaoKosei ShinoharaKeigo SugisawaKengo UramotoTae Igarashi-YokoiTakeshi YoshidaKyoko Ohno-MatsuiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hiroyuki Takahashi Noriko Nakao Kosei Shinohara Keigo Sugisawa Kengo Uramoto Tae Igarashi-Yokoi Takeshi Yoshida Kyoko Ohno-Matsui Posterior vitreous detachment and paravascular retinoschisis in highly myopic young patients detected by ultra-widefield OCT
description	Abstract The purpose of this study was to determine the relationship between a posterior vitreous detachment (PVD) and retinoschisis (RS) in 73 highly myopic (HM) young patients age 16.4 ± 6.9 years and 24 non-HM children age 8.4 ± 1.5 years. The presence of the paravascular retinal abnormalities was determined in the images obtained by a ultra-widefield OCT (UWF OCT) instrument with an image field of 23 × 20 mm. The results showed that a partial PVD was detected in 15 (21%) of the HM patients, and the number increased significantly with increasing age (P = 0.02). PVDs of any type were not found in the non-HM eyes. The number of microvascular folds also increased with age in the HM patients (P = 0.03). Medium-reflective columnar tissues were present between the detached vitreous and inner retinal surface in 4 (5%) eyes of the HM patients. Myopic RS was found in 3 (4%) HM patients in the paravascular area but not in the macular area. These results suggest that early partial PVD may play a role in pathological and proliferative vitreous changes of HM eyes. An intense vitreoretinal traction with bridging tissues may cause the various paravascular retinal abnormalities. In HM eyes, paravascular RS is already present at an early age which may progress to macular RS with aging.
format	article
author	Hiroyuki Takahashi Noriko Nakao Kosei Shinohara Keigo Sugisawa Kengo Uramoto Tae Igarashi-Yokoi Takeshi Yoshida Kyoko Ohno-Matsui
author_facet	Hiroyuki Takahashi Noriko Nakao Kosei Shinohara Keigo Sugisawa Kengo Uramoto Tae Igarashi-Yokoi Takeshi Yoshida Kyoko Ohno-Matsui
author_sort	Hiroyuki Takahashi
title	Posterior vitreous detachment and paravascular retinoschisis in highly myopic young patients detected by ultra-widefield OCT
title_short	Posterior vitreous detachment and paravascular retinoschisis in highly myopic young patients detected by ultra-widefield OCT
title_full	Posterior vitreous detachment and paravascular retinoschisis in highly myopic young patients detected by ultra-widefield OCT
title_fullStr	Posterior vitreous detachment and paravascular retinoschisis in highly myopic young patients detected by ultra-widefield OCT
title_full_unstemmed	Posterior vitreous detachment and paravascular retinoschisis in highly myopic young patients detected by ultra-widefield OCT
title_sort	posterior vitreous detachment and paravascular retinoschisis in highly myopic young patients detected by ultra-widefield oct
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/2f97b309f5ca4fe9845a335066cd0db9
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Posterior vitreous detachment and paravascular retinoschisis in highly myopic young patients detected by ultra-widefield OCT

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