Molecular insight into RNA polymerase I promoter recognition and promoter melting

RNA polymerase I (Pol I) catalyses the transcription of pre-ribosomal RNA and for transcription initiation Pol I assembles with core factor and Rrn3 on the rDNA core promoter. Here the authors provide insights into the molecular mechanism of promoter opening by Pol I by determining the cryo-EM struc...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yashar Sadian, Florence Baudin, Lucas Tafur, Brice Murciano, Rene Wetzel, Felix Weis, Christoph W. Müller
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2f9e5295c8a243efb432a2a00bad71af
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:2f9e5295c8a243efb432a2a00bad71af
record_format	dspace
spelling	oai:doaj.org-article:2f9e5295c8a243efb432a2a00bad71af2021-12-02T17:32:10ZMolecular insight into RNA polymerase I promoter recognition and promoter melting10.1038/s41467-019-13510-w2041-1723https://doaj.org/article/2f9e5295c8a243efb432a2a00bad71af2019-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13510-whttps://doaj.org/toc/2041-1723RNA polymerase I (Pol I) catalyses the transcription of pre-ribosomal RNA and for transcription initiation Pol I assembles with core factor and Rrn3 on the rDNA core promoter. Here the authors provide insights into the molecular mechanism of promoter opening by Pol I by determining the cryo-EM structures of two closed, two intermediate and two open Pol I pre-initiation complexes.Yashar SadianFlorence BaudinLucas TafurBrice MurcianoRene WetzelFelix WeisChristoph W. MüllerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yashar Sadian Florence Baudin Lucas Tafur Brice Murciano Rene Wetzel Felix Weis Christoph W. Müller Molecular insight into RNA polymerase I promoter recognition and promoter melting
description	RNA polymerase I (Pol I) catalyses the transcription of pre-ribosomal RNA and for transcription initiation Pol I assembles with core factor and Rrn3 on the rDNA core promoter. Here the authors provide insights into the molecular mechanism of promoter opening by Pol I by determining the cryo-EM structures of two closed, two intermediate and two open Pol I pre-initiation complexes.
format	article
author	Yashar Sadian Florence Baudin Lucas Tafur Brice Murciano Rene Wetzel Felix Weis Christoph W. Müller
author_facet	Yashar Sadian Florence Baudin Lucas Tafur Brice Murciano Rene Wetzel Felix Weis Christoph W. Müller
author_sort	Yashar Sadian
title	Molecular insight into RNA polymerase I promoter recognition and promoter melting
title_short	Molecular insight into RNA polymerase I promoter recognition and promoter melting
title_full	Molecular insight into RNA polymerase I promoter recognition and promoter melting
title_fullStr	Molecular insight into RNA polymerase I promoter recognition and promoter melting
title_full_unstemmed	Molecular insight into RNA polymerase I promoter recognition and promoter melting
title_sort	molecular insight into rna polymerase i promoter recognition and promoter melting
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/2f9e5295c8a243efb432a2a00bad71af
work_keys_str_mv	AT yasharsadian molecularinsightintornapolymeraseipromoterrecognitionandpromotermelting AT florencebaudin molecularinsightintornapolymeraseipromoterrecognitionandpromotermelting AT lucastafur molecularinsightintornapolymeraseipromoterrecognitionandpromotermelting AT bricemurciano molecularinsightintornapolymeraseipromoterrecognitionandpromotermelting AT renewetzel molecularinsightintornapolymeraseipromoterrecognitionandpromotermelting AT felixweis molecularinsightintornapolymeraseipromoterrecognitionandpromotermelting AT christophwmuller molecularinsightintornapolymeraseipromoterrecognitionandpromotermelting
_version_	1718380358906413056

Molecular insight into RNA polymerase I promoter recognition and promoter melting

Ejemplares similares