Samarium(II) folding cascades involving hydrogen atom transfer for the synthesis of complex polycycles

Diversity-oriented synthesis is a valuable strategy to construct complex molecules of medicinal interest. Here, the authors show a folding cascade strategy to convert linear substrates into polycyclic compounds with multiple stereocentres by combining the reductive chemistry of SmI2 with 1,5-hydroge...

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Autores principales:	Mateusz P. Plesniak, Monserrat H. Garduño-Castro, Philipp Lenz, Xavier Just-Baringo, David J. Procter
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2f9ec65858a9472abcce7a85ceee9e44
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spelling	oai:doaj.org-article:2f9ec65858a9472abcce7a85ceee9e442021-12-02T16:56:57ZSamarium(II) folding cascades involving hydrogen atom transfer for the synthesis of complex polycycles10.1038/s41467-018-07194-x2041-1723https://doaj.org/article/2f9ec65858a9472abcce7a85ceee9e442018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07194-xhttps://doaj.org/toc/2041-1723Diversity-oriented synthesis is a valuable strategy to construct complex molecules of medicinal interest. Here, the authors show a folding cascade strategy to convert linear substrates into polycyclic compounds with multiple stereocentres by combining the reductive chemistry of SmI2 with 1,5-hydrogen atom transfer.Mateusz P. PlesniakMonserrat H. Garduño-CastroPhilipp LenzXavier Just-BaringoDavid J. ProcterNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Mateusz P. Plesniak Monserrat H. Garduño-Castro Philipp Lenz Xavier Just-Baringo David J. Procter Samarium(II) folding cascades involving hydrogen atom transfer for the synthesis of complex polycycles
description	Diversity-oriented synthesis is a valuable strategy to construct complex molecules of medicinal interest. Here, the authors show a folding cascade strategy to convert linear substrates into polycyclic compounds with multiple stereocentres by combining the reductive chemistry of SmI2 with 1,5-hydrogen atom transfer.
format	article
author	Mateusz P. Plesniak Monserrat H. Garduño-Castro Philipp Lenz Xavier Just-Baringo David J. Procter
author_facet	Mateusz P. Plesniak Monserrat H. Garduño-Castro Philipp Lenz Xavier Just-Baringo David J. Procter
author_sort	Mateusz P. Plesniak
title	Samarium(II) folding cascades involving hydrogen atom transfer for the synthesis of complex polycycles
title_short	Samarium(II) folding cascades involving hydrogen atom transfer for the synthesis of complex polycycles
title_full	Samarium(II) folding cascades involving hydrogen atom transfer for the synthesis of complex polycycles
title_fullStr	Samarium(II) folding cascades involving hydrogen atom transfer for the synthesis of complex polycycles
title_full_unstemmed	Samarium(II) folding cascades involving hydrogen atom transfer for the synthesis of complex polycycles
title_sort	samarium(ii) folding cascades involving hydrogen atom transfer for the synthesis of complex polycycles
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/2f9ec65858a9472abcce7a85ceee9e44
work_keys_str_mv	AT mateuszpplesniak samariumiifoldingcascadesinvolvinghydrogenatomtransferforthesynthesisofcomplexpolycycles AT monserrathgardunocastro samariumiifoldingcascadesinvolvinghydrogenatomtransferforthesynthesisofcomplexpolycycles AT philipplenz samariumiifoldingcascadesinvolvinghydrogenatomtransferforthesynthesisofcomplexpolycycles AT xavierjustbaringo samariumiifoldingcascadesinvolvinghydrogenatomtransferforthesynthesisofcomplexpolycycles AT davidjprocter samariumiifoldingcascadesinvolvinghydrogenatomtransferforthesynthesisofcomplexpolycycles
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Samarium(II) folding cascades involving hydrogen atom transfer for the synthesis of complex polycycles

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