A fully orthogonal system for protein synthesis in bacterial cells

Ribosome engineering is an emerging powerful approach for synthetic protein synthesis. Here the authors invert the Ribo-T system, using the engineered ribosome to translate the proteome while the native ribosome translates specific mRNA.

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Autores principales:	Nikolay A. Aleksashin, Teresa Szal, Anne E. d’Aquino, Michael C. Jewett, Nora Vázquez-Laslop, Alexander S. Mankin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2fa4b8a9829c4319b8a0ec1c4381a811
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spelling	oai:doaj.org-article:2fa4b8a9829c4319b8a0ec1c4381a8112021-12-02T15:39:21ZA fully orthogonal system for protein synthesis in bacterial cells10.1038/s41467-020-15756-12041-1723https://doaj.org/article/2fa4b8a9829c4319b8a0ec1c4381a8112020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15756-1https://doaj.org/toc/2041-1723Ribosome engineering is an emerging powerful approach for synthetic protein synthesis. Here the authors invert the Ribo-T system, using the engineered ribosome to translate the proteome while the native ribosome translates specific mRNA.Nikolay A. AleksashinTeresa SzalAnne E. d’AquinoMichael C. JewettNora Vázquez-LaslopAlexander S. MankinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Nikolay A. Aleksashin Teresa Szal Anne E. d’Aquino Michael C. Jewett Nora Vázquez-Laslop Alexander S. Mankin A fully orthogonal system for protein synthesis in bacterial cells
description	Ribosome engineering is an emerging powerful approach for synthetic protein synthesis. Here the authors invert the Ribo-T system, using the engineered ribosome to translate the proteome while the native ribosome translates specific mRNA.
format	article
author	Nikolay A. Aleksashin Teresa Szal Anne E. d’Aquino Michael C. Jewett Nora Vázquez-Laslop Alexander S. Mankin
author_facet	Nikolay A. Aleksashin Teresa Szal Anne E. d’Aquino Michael C. Jewett Nora Vázquez-Laslop Alexander S. Mankin
author_sort	Nikolay A. Aleksashin
title	A fully orthogonal system for protein synthesis in bacterial cells
title_short	A fully orthogonal system for protein synthesis in bacterial cells
title_full	A fully orthogonal system for protein synthesis in bacterial cells
title_fullStr	A fully orthogonal system for protein synthesis in bacterial cells
title_full_unstemmed	A fully orthogonal system for protein synthesis in bacterial cells
title_sort	fully orthogonal system for protein synthesis in bacterial cells
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/2fa4b8a9829c4319b8a0ec1c4381a811
work_keys_str_mv	AT nikolayaaleksashin afullyorthogonalsystemforproteinsynthesisinbacterialcells AT teresaszal afullyorthogonalsystemforproteinsynthesisinbacterialcells AT anneedaquino afullyorthogonalsystemforproteinsynthesisinbacterialcells AT michaelcjewett afullyorthogonalsystemforproteinsynthesisinbacterialcells AT noravazquezlaslop afullyorthogonalsystemforproteinsynthesisinbacterialcells AT alexandersmankin afullyorthogonalsystemforproteinsynthesisinbacterialcells AT nikolayaaleksashin fullyorthogonalsystemforproteinsynthesisinbacterialcells AT teresaszal fullyorthogonalsystemforproteinsynthesisinbacterialcells AT anneedaquino fullyorthogonalsystemforproteinsynthesisinbacterialcells AT michaelcjewett fullyorthogonalsystemforproteinsynthesisinbacterialcells AT noravazquezlaslop fullyorthogonalsystemforproteinsynthesisinbacterialcells AT alexandersmankin fullyorthogonalsystemforproteinsynthesisinbacterialcells
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A fully orthogonal system for protein synthesis in bacterial cells

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