Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells
Zika virus (ZIKV) infection can cause congenital Zika syndrome (CZS), but the underlying mechanisms are poorly understood. Here, the authors generate neural progenitor cells from dizygotic twins with a discordant phenotype regarding CZS and study their response to ZIKV infection.
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Nature Portfolio
2018
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oai:doaj.org-article:2fae1218b8954f70ace6659a61a3d04f2021-12-02T17:32:33ZDiscordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells10.1038/s41467-017-02790-92041-1723https://doaj.org/article/2fae1218b8954f70ace6659a61a3d04f2018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-02790-9https://doaj.org/toc/2041-1723Zika virus (ZIKV) infection can cause congenital Zika syndrome (CZS), but the underlying mechanisms are poorly understood. Here, the authors generate neural progenitor cells from dizygotic twins with a discordant phenotype regarding CZS and study their response to ZIKV infection.Luiz Carlos Caires-JúniorErnesto GoulartUirá Souto MeloBruno Henrique Silva AraujoLucas AlviziAlessandra Soares-SchanoskiDanyllo Felipe de OliveiraGerson Shigeru KobayashiKarina Griesi-OliveiraCamila Manso MussoMurilo Sena AmaralLucas Ferreira daSilvaRenato Mancini AstraySandra Fernanda Suárez-PatiñoDaniella Cristina VentiniSérgio Gomes da SilvaGuilherme Lopes YamamotoSuzana EzquinaMichel Satya NaslavskyKayque Alves Telles-SilvaKarina WeinmannVanessa van der LindenHelio van der LindenJoão Ricardo Mendes de OliveiraNivia Maria Rodrigues ArraisAdriana MeloThalita FigueiredoSilvana SantosJoanna Goes Castro MeiraSaulo Duarte PassosRoque Pacheco de AlmeidaAna Jovina Barreto BispoEsper Abrão CavalheiroJorge KalilEdécio Cunha-NetoHelder NakayaRobert Andreata-SantosLuis Carlos de Souza FerreiraSergio Verjovski-AlmeidaPaulo Lee HoMaria Rita Passos-BuenoMayana ZatzNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018) |
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Science Q Luiz Carlos Caires-Júnior Ernesto Goulart Uirá Souto Melo Bruno Henrique Silva Araujo Lucas Alvizi Alessandra Soares-Schanoski Danyllo Felipe de Oliveira Gerson Shigeru Kobayashi Karina Griesi-Oliveira Camila Manso Musso Murilo Sena Amaral Lucas Ferreira daSilva Renato Mancini Astray Sandra Fernanda Suárez-Patiño Daniella Cristina Ventini Sérgio Gomes da Silva Guilherme Lopes Yamamoto Suzana Ezquina Michel Satya Naslavsky Kayque Alves Telles-Silva Karina Weinmann Vanessa van der Linden Helio van der Linden João Ricardo Mendes de Oliveira Nivia Maria Rodrigues Arrais Adriana Melo Thalita Figueiredo Silvana Santos Joanna Goes Castro Meira Saulo Duarte Passos Roque Pacheco de Almeida Ana Jovina Barreto Bispo Esper Abrão Cavalheiro Jorge Kalil Edécio Cunha-Neto Helder Nakaya Robert Andreata-Santos Luis Carlos de Souza Ferreira Sergio Verjovski-Almeida Paulo Lee Ho Maria Rita Passos-Bueno Mayana Zatz Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells |
| description |
Zika virus (ZIKV) infection can cause congenital Zika syndrome (CZS), but the underlying mechanisms are poorly understood. Here, the authors generate neural progenitor cells from dizygotic twins with a discordant phenotype regarding CZS and study their response to ZIKV infection. |
| format |
article |
| author |
Luiz Carlos Caires-Júnior Ernesto Goulart Uirá Souto Melo Bruno Henrique Silva Araujo Lucas Alvizi Alessandra Soares-Schanoski Danyllo Felipe de Oliveira Gerson Shigeru Kobayashi Karina Griesi-Oliveira Camila Manso Musso Murilo Sena Amaral Lucas Ferreira daSilva Renato Mancini Astray Sandra Fernanda Suárez-Patiño Daniella Cristina Ventini Sérgio Gomes da Silva Guilherme Lopes Yamamoto Suzana Ezquina Michel Satya Naslavsky Kayque Alves Telles-Silva Karina Weinmann Vanessa van der Linden Helio van der Linden João Ricardo Mendes de Oliveira Nivia Maria Rodrigues Arrais Adriana Melo Thalita Figueiredo Silvana Santos Joanna Goes Castro Meira Saulo Duarte Passos Roque Pacheco de Almeida Ana Jovina Barreto Bispo Esper Abrão Cavalheiro Jorge Kalil Edécio Cunha-Neto Helder Nakaya Robert Andreata-Santos Luis Carlos de Souza Ferreira Sergio Verjovski-Almeida Paulo Lee Ho Maria Rita Passos-Bueno Mayana Zatz |
| author_facet |
Luiz Carlos Caires-Júnior Ernesto Goulart Uirá Souto Melo Bruno Henrique Silva Araujo Lucas Alvizi Alessandra Soares-Schanoski Danyllo Felipe de Oliveira Gerson Shigeru Kobayashi Karina Griesi-Oliveira Camila Manso Musso Murilo Sena Amaral Lucas Ferreira daSilva Renato Mancini Astray Sandra Fernanda Suárez-Patiño Daniella Cristina Ventini Sérgio Gomes da Silva Guilherme Lopes Yamamoto Suzana Ezquina Michel Satya Naslavsky Kayque Alves Telles-Silva Karina Weinmann Vanessa van der Linden Helio van der Linden João Ricardo Mendes de Oliveira Nivia Maria Rodrigues Arrais Adriana Melo Thalita Figueiredo Silvana Santos Joanna Goes Castro Meira Saulo Duarte Passos Roque Pacheco de Almeida Ana Jovina Barreto Bispo Esper Abrão Cavalheiro Jorge Kalil Edécio Cunha-Neto Helder Nakaya Robert Andreata-Santos Luis Carlos de Souza Ferreira Sergio Verjovski-Almeida Paulo Lee Ho Maria Rita Passos-Bueno Mayana Zatz |
| author_sort |
Luiz Carlos Caires-Júnior |
| title |
Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells |
| title_short |
Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells |
| title_full |
Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells |
| title_fullStr |
Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells |
| title_full_unstemmed |
Discordant congenital Zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells |
| title_sort |
discordant congenital zika syndrome twins show differential in vitro viral susceptibility of neural progenitor cells |
| publisher |
Nature Portfolio |
| publishDate |
2018 |
| url |
https://doaj.org/article/2fae1218b8954f70ace6659a61a3d04f |
| work_keys_str_mv |
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