Genetic variation in the β2-adrenocepter gene is associated with susceptibility to bacterial meningitis in adults.

Genetic variation in the β2-adrenocepter gene is associated with susceptibility to bacterial meningitis in adults.

Recently, the biased β2-adrenoceptor/β-arrestin pathway was shown to play a pivotal role in crossing of the blood brain barrier by Neisseria meningitidis. We hypothesized that genetic variation in the β2-adrenoceptor gene (ADRB2) may influence susceptibility to bacterial meningitis. In a prospective...

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Autores principales: Kirsten S Adriani, Matthijs C Brouwer, Frank Baas, Aeilko H Zwinderman, Arie van der Ende, Diederik van de Beek
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2012
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2faff4bf605d4750a206b16a451db838
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