Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment
AnnexinV has been shown to bind phosphatidylserine expressed by chemotherapy-induced apoptotic cells increasing their immunogeneicity. Here, the authors demonstrate in a preclinical tumor model that fusing tumor-antigen peptide to Annexin V enhances its efficacy when administered after chemotherapy...
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Nature Portfolio
2020
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/2fb1fbb0de664cbdac06f9837a479b3c |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|