Type I interferon protects against pneumococcal invasive disease by inhibiting bacterial transmigration across the lung.

Streptococcus pneumoniae infection is a leading cause of bacterial pneumonia, sepsis and meningitis and is associated with high morbidity and mortality. Type I interferon (IFN-I), whose contribution to antiviral and intracellular bacterial immunity is well established, is also elicited during pneumo...

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Bibliographic Details
Main Authors: Kim S LeMessurier, Hans Häcker, Liying Chi, Elaine Tuomanen, Vanessa Redecke
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
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Online Access:https://doaj.org/article/2fba4f496af54d92a578a2b456dc1feb
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