Insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance

Electrochemiluminescence (ECL) is a leading technique in biosensing. Here the authors identify an ECL generation mechanism near the electrode surface, which they exploit in combination with the use of branched amine coreactants to improve the ECL signal beyond the state-of-the-art immunoassays.

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Autores principales:	Alessandra Zanut, Andrea Fiorani, Sofia Canola, Toshiro Saito, Nicole Ziebart, Stefania Rapino, Sara Rebeccani, Antonio Barbon, Takashi Irie, Hans-Peter Josel, Fabrizia Negri, Massimo Marcaccio, Michaela Windfuhr, Kyoko Imai, Giovanni Valenti, Francesco Paolucci
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2fc71afbac274092a7b6e108eed11b49
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spelling	oai:doaj.org-article:2fc71afbac274092a7b6e108eed11b492021-12-02T15:49:52ZInsights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance10.1038/s41467-020-16476-22041-1723https://doaj.org/article/2fc71afbac274092a7b6e108eed11b492020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16476-2https://doaj.org/toc/2041-1723Electrochemiluminescence (ECL) is a leading technique in biosensing. Here the authors identify an ECL generation mechanism near the electrode surface, which they exploit in combination with the use of branched amine coreactants to improve the ECL signal beyond the state-of-the-art immunoassays.Alessandra ZanutAndrea FioraniSofia CanolaToshiro SaitoNicole ZiebartStefania RapinoSara RebeccaniAntonio BarbonTakashi IrieHans-Peter JoselFabrizia NegriMassimo MarcaccioMichaela WindfuhrKyoko ImaiGiovanni ValentiFrancesco PaolucciNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alessandra Zanut Andrea Fiorani Sofia Canola Toshiro Saito Nicole Ziebart Stefania Rapino Sara Rebeccani Antonio Barbon Takashi Irie Hans-Peter Josel Fabrizia Negri Massimo Marcaccio Michaela Windfuhr Kyoko Imai Giovanni Valenti Francesco Paolucci Insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance
description	Electrochemiluminescence (ECL) is a leading technique in biosensing. Here the authors identify an ECL generation mechanism near the electrode surface, which they exploit in combination with the use of branched amine coreactants to improve the ECL signal beyond the state-of-the-art immunoassays.
format	article
author	Alessandra Zanut Andrea Fiorani Sofia Canola Toshiro Saito Nicole Ziebart Stefania Rapino Sara Rebeccani Antonio Barbon Takashi Irie Hans-Peter Josel Fabrizia Negri Massimo Marcaccio Michaela Windfuhr Kyoko Imai Giovanni Valenti Francesco Paolucci
author_facet	Alessandra Zanut Andrea Fiorani Sofia Canola Toshiro Saito Nicole Ziebart Stefania Rapino Sara Rebeccani Antonio Barbon Takashi Irie Hans-Peter Josel Fabrizia Negri Massimo Marcaccio Michaela Windfuhr Kyoko Imai Giovanni Valenti Francesco Paolucci
author_sort	Alessandra Zanut
title	Insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance
title_short	Insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance
title_full	Insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance
title_fullStr	Insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance
title_full_unstemmed	Insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance
title_sort	insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/2fc71afbac274092a7b6e108eed11b49
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Insights into the mechanism of coreactant electrochemiluminescence facilitating enhanced bioanalytical performance

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