Relationship between hemagglutinin stability and influenza virus persistence after exposure to low pH or supraphysiological heating.
The hemagglutinin (HA) surface glycoprotein is triggered by endosomal low pH to cause membrane fusion during influenza A virus (IAV) entry yet must remain sufficiently stable to avoid premature activation during virion transit between cells and hosts. HA activation pH and/or virion inactivation pH v...
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Auteurs principaux: | Guohua Yang, Chet R Ojha, Charles J Russell |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2021
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Accès en ligne: | https://doaj.org/article/2fd411c54790405ba57981eea02ba9eb |
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