Nucleophilic trifluoromethoxylation of alkyl halides without silver

Trifluoromethyl ethers are important bioactive targets in pharmaceuticals and agrochemicals, however, their synthesis is often not straightforward. Here, the authors disclose a reagent for the nucleophilic trifluoromethoxylation of alkyl halides without silver and under mild conditions.

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Autores principales:	Yan Li, Yang Yang, Jinrui Xin, Pingping Tang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2fd67ad25c414fd5b4acce3564b603f0
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spelling	oai:doaj.org-article:2fd67ad25c414fd5b4acce3564b603f02021-12-02T14:40:30ZNucleophilic trifluoromethoxylation of alkyl halides without silver10.1038/s41467-020-14598-12041-1723https://doaj.org/article/2fd67ad25c414fd5b4acce3564b603f02020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14598-1https://doaj.org/toc/2041-1723Trifluoromethyl ethers are important bioactive targets in pharmaceuticals and agrochemicals, however, their synthesis is often not straightforward. Here, the authors disclose a reagent for the nucleophilic trifluoromethoxylation of alkyl halides without silver and under mild conditions.Yan LiYang YangJinrui XinPingping TangNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-7 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yan Li Yang Yang Jinrui Xin Pingping Tang Nucleophilic trifluoromethoxylation of alkyl halides without silver
description	Trifluoromethyl ethers are important bioactive targets in pharmaceuticals and agrochemicals, however, their synthesis is often not straightforward. Here, the authors disclose a reagent for the nucleophilic trifluoromethoxylation of alkyl halides without silver and under mild conditions.
format	article
author	Yan Li Yang Yang Jinrui Xin Pingping Tang
author_facet	Yan Li Yang Yang Jinrui Xin Pingping Tang
author_sort	Yan Li
title	Nucleophilic trifluoromethoxylation of alkyl halides without silver
title_short	Nucleophilic trifluoromethoxylation of alkyl halides without silver
title_full	Nucleophilic trifluoromethoxylation of alkyl halides without silver
title_fullStr	Nucleophilic trifluoromethoxylation of alkyl halides without silver
title_full_unstemmed	Nucleophilic trifluoromethoxylation of alkyl halides without silver
title_sort	nucleophilic trifluoromethoxylation of alkyl halides without silver
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/2fd67ad25c414fd5b4acce3564b603f0
work_keys_str_mv	AT yanli nucleophilictrifluoromethoxylationofalkylhalideswithoutsilver AT yangyang nucleophilictrifluoromethoxylationofalkylhalideswithoutsilver AT jinruixin nucleophilictrifluoromethoxylationofalkylhalideswithoutsilver AT pingpingtang nucleophilictrifluoromethoxylationofalkylhalideswithoutsilver
_version_	1718390226719604736

Nucleophilic trifluoromethoxylation of alkyl halides without silver

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