The Polyphosphate Kinase Gene <italic toggle="yes">ppk2</italic> Is Required for <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content> Inorganic Polyphosphate Regulation and Virulence
ABSTRACT The Mycobacterium tuberculosis gene Rv3232c/MT3329 (ppk2) encodes a class II polyphosphate kinase, which hydrolyzes inorganic polyphosphate (poly P) to synthesize GTP. We assessed the role of ppk2 in M. tuberculosis poly P regulation, antibiotic tolerance, and virulence. A ppk2-deficient mu...
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| Auteurs principaux: | , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
American Society for Microbiology
2013
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| Accès en ligne: | https://doaj.org/article/2fdabfa3f8a04588a39a75d7acda6b0b |
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