Role of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension

Henny JM Beckers, Jan SAG Schouten, Carroll AB WebersUniversity Eye Clinic, Maastricht, The NetherlandsAbstract: Brinzolamide 1%/timolol 0.5% is a new fixed-combination for the treatment of open-angle glaucoma or ocular hypertension. Brinzolamide/timolol has a favorable safety profile, with an incid...

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Autores principales: Henny JM Beckers, Jan SAG Schouten, Carroll AB Webers
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2009
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Acceso en línea:https://doaj.org/article/2fdc04c24a554665b28e6ef0fd5cc3bf
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spelling oai:doaj.org-article:2fdc04c24a554665b28e6ef0fd5cc3bf2021-12-02T07:52:06ZRole of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension1177-54671177-5483https://doaj.org/article/2fdc04c24a554665b28e6ef0fd5cc3bf2009-10-01T00:00:00Zhttp://www.dovepress.com/role-of-fixed-combination-brinzolamide-1timolol-05-in-the-treatment-of-a3655https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Henny JM Beckers, Jan SAG Schouten, Carroll AB WebersUniversity Eye Clinic, Maastricht, The NetherlandsAbstract: Brinzolamide 1%/timolol 0.5% is a new fixed-combination for the treatment of open-angle glaucoma or ocular hypertension. Brinzolamide/timolol has a favorable safety profile, with an incidence of ocular burning and stinging <5%. Published data show that brinzolamide 1%/timolol 0.5% and dorzolamide 2%/timolol 0.5% have similar efficacies for lowering intraocular pressure (IOP). There is some evidence that brinzolamide/timolol may be more comfortable. Although patients receiving brinzolamide/timolol may experience more blurred vision on instillation, some data show a preference for brinzolamide/timolol over dorzolamide/timolol. Although available data to assess the role of brinzolamide/timolol in daily clinical practice are still limited, these first results suggest the agent to be a reasonable alternative for patients who do not reach target IOP with monotherapy. Henny JM BeckersJan SAG SchoutenCarroll AB WebersDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2009, Iss default, Pp 593-599 (2009)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Henny JM Beckers
Jan SAG Schouten
Carroll AB Webers
Role of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
description Henny JM Beckers, Jan SAG Schouten, Carroll AB WebersUniversity Eye Clinic, Maastricht, The NetherlandsAbstract: Brinzolamide 1%/timolol 0.5% is a new fixed-combination for the treatment of open-angle glaucoma or ocular hypertension. Brinzolamide/timolol has a favorable safety profile, with an incidence of ocular burning and stinging <5%. Published data show that brinzolamide 1%/timolol 0.5% and dorzolamide 2%/timolol 0.5% have similar efficacies for lowering intraocular pressure (IOP). There is some evidence that brinzolamide/timolol may be more comfortable. Although patients receiving brinzolamide/timolol may experience more blurred vision on instillation, some data show a preference for brinzolamide/timolol over dorzolamide/timolol. Although available data to assess the role of brinzolamide/timolol in daily clinical practice are still limited, these first results suggest the agent to be a reasonable alternative for patients who do not reach target IOP with monotherapy.
format article
author Henny JM Beckers
Jan SAG Schouten
Carroll AB Webers
author_facet Henny JM Beckers
Jan SAG Schouten
Carroll AB Webers
author_sort Henny JM Beckers
title Role of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
title_short Role of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
title_full Role of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
title_fullStr Role of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
title_full_unstemmed Role of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
title_sort role of fixed-combination brinzolamide 1%/timolol 0.5% in the treatment of elevated intraocular pressure in open-angle glaucoma and ocular hypertension
publisher Dove Medical Press
publishDate 2009
url https://doaj.org/article/2fdc04c24a554665b28e6ef0fd5cc3bf
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AT jansagschouten roleoffixedcombinationbrinzolamide1timolol05inthetreatmentofelevatedintraocularpressureinopenangleglaucomaandocularhypertension
AT carrollabwebers roleoffixedcombinationbrinzolamide1timolol05inthetreatmentofelevatedintraocularpressureinopenangleglaucomaandocularhypertension
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