INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION

The article is devoted to the study of activity of lipid peroxidation processes and their influence on oxygen-transport properties of hemoglobin in erythrocytes of peripheral blood of pregnant women with cytomegalovirus infection. Activation of lipid peroxidation processes in pregnant women with cyt...

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Autores principales: N. A. Ishutina, I. A. Andrievskaya, O. L. Kutepova, A. G. Mironenko
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2014
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spelling oai:doaj.org-article:2fe204c912e64308875216ddbeb95d902021-11-23T06:14:30ZINFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION2541-94202587-9596https://doaj.org/article/2fe204c912e64308875216ddbeb95d902014-04-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/1731https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The article is devoted to the study of activity of lipid peroxidation processes and their influence on oxygen-transport properties of hemoglobin in erythrocytes of peripheral blood of pregnant women with cytomegalovirus infection. Activation of lipid peroxidation processes in pregnant women with cytomegalovirus infection determined by the contents of TBA-active products is accompanied by accumulation of cytotoxic factors - arachidonic acid (1 trimester - up by 31 %, 11 trimester - up by 68 %, 111 trimester - up by 41 %) and lysophosphatidylcholine (1 trimester - up by 85 %, 11 trimester - up by 55 %, 111 trimester - up by 13 %), causes disorders of oxygen-transport properties of hemoglobin in erythrocytes (decrease of total erythrocytes and hemoglobin count), more than double increase of indices of thermolabile hemoglobin at slight decrease of oxyhemoglobin, increase of methemoglobin (1 trimester - up by 60 %, 11 trimester - up by 25 %, 111 trimester - up by 16 %, in comparison with control), that causes decrease of transportation and delivery of oxygen to the tissues and can be the reason of hypoxia.N. A. IshutinaI. A. AndrievskayaO. L. KutepovaA. G. MironenkoScientific Сentre for Family Health and Human Reproduction Problemsarticlepregnancycytomegalovirus infectionlipids peroxidationhemoglobinScienceQRUActa Biomedica Scientifica, Vol 0, Iss 2, Pp 24-28 (2014)
institution DOAJ
collection DOAJ
language RU
topic pregnancy
cytomegalovirus infection
lipids peroxidation
hemoglobin
Science
Q
spellingShingle pregnancy
cytomegalovirus infection
lipids peroxidation
hemoglobin
Science
Q
N. A. Ishutina
I. A. Andrievskaya
O. L. Kutepova
A. G. Mironenko
INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION
description The article is devoted to the study of activity of lipid peroxidation processes and their influence on oxygen-transport properties of hemoglobin in erythrocytes of peripheral blood of pregnant women with cytomegalovirus infection. Activation of lipid peroxidation processes in pregnant women with cytomegalovirus infection determined by the contents of TBA-active products is accompanied by accumulation of cytotoxic factors - arachidonic acid (1 trimester - up by 31 %, 11 trimester - up by 68 %, 111 trimester - up by 41 %) and lysophosphatidylcholine (1 trimester - up by 85 %, 11 trimester - up by 55 %, 111 trimester - up by 13 %), causes disorders of oxygen-transport properties of hemoglobin in erythrocytes (decrease of total erythrocytes and hemoglobin count), more than double increase of indices of thermolabile hemoglobin at slight decrease of oxyhemoglobin, increase of methemoglobin (1 trimester - up by 60 %, 11 trimester - up by 25 %, 111 trimester - up by 16 %, in comparison with control), that causes decrease of transportation and delivery of oxygen to the tissues and can be the reason of hypoxia.
format article
author N. A. Ishutina
I. A. Andrievskaya
O. L. Kutepova
A. G. Mironenko
author_facet N. A. Ishutina
I. A. Andrievskaya
O. L. Kutepova
A. G. Mironenko
author_sort N. A. Ishutina
title INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION
title_short INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION
title_full INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION
title_fullStr INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION
title_full_unstemmed INFLUENCE OF LIPID PEROXIDATION PROCESSES ON OXYGEN-TRANSPORT PROPERTIES OF HEMOGLOBIN IN ERYTHROCYTES OF PERIPHERAL BLOOD OF PREGNANT WOMEN WITH CYTOMEGALOVIRUS INFECTION
title_sort influence of lipid peroxidation processes on oxygen-transport properties of hemoglobin in erythrocytes of peripheral blood of pregnant women with cytomegalovirus infection
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2014
url https://doaj.org/article/2fe204c912e64308875216ddbeb95d90
work_keys_str_mv AT naishutina influenceoflipidperoxidationprocessesonoxygentransportpropertiesofhemoglobininerythrocytesofperipheralbloodofpregnantwomenwithcytomegalovirusinfection
AT iaandrievskaya influenceoflipidperoxidationprocessesonoxygentransportpropertiesofhemoglobininerythrocytesofperipheralbloodofpregnantwomenwithcytomegalovirusinfection
AT olkutepova influenceoflipidperoxidationprocessesonoxygentransportpropertiesofhemoglobininerythrocytesofperipheralbloodofpregnantwomenwithcytomegalovirusinfection
AT agmironenko influenceoflipidperoxidationprocessesonoxygentransportpropertiesofhemoglobininerythrocytesofperipheralbloodofpregnantwomenwithcytomegalovirusinfection
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