Membrane bending occurs at all stages of clathrin-coat assembly and defines endocytic dynamics

Two distinct and opposing models for clathrin-mediated endocytosis have been inferred from EM and structural biology data. Here the authors develop an optical method to directly visualize membrane-bending dynamics and show that coat assembly accommodates membrane bending during or after the assembly...

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Autores principales:	Brandon L. Scott, Kem A. Sochacki, Shalini T. Low-Nam, Elizabeth M. Bailey, QuocAhn Luu, Amy Hor, Andrea M. Dickey, Steve Smith, Jason G. Kerkvliet, Justin W. Taraska, Adam D. Hoppe
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/2fe8db89130d4f17aa027a673b9544f1
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spelling	oai:doaj.org-article:2fe8db89130d4f17aa027a673b9544f12021-12-02T14:40:30ZMembrane bending occurs at all stages of clathrin-coat assembly and defines endocytic dynamics10.1038/s41467-018-02818-82041-1723https://doaj.org/article/2fe8db89130d4f17aa027a673b9544f12018-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-02818-8https://doaj.org/toc/2041-1723Two distinct and opposing models for clathrin-mediated endocytosis have been inferred from EM and structural biology data. Here the authors develop an optical method to directly visualize membrane-bending dynamics and show that coat assembly accommodates membrane bending during or after the assembly of the clathrin lattice, which is not predicted by either model.Brandon L. ScottKem A. SochackiShalini T. Low-NamElizabeth M. BaileyQuocAhn LuuAmy HorAndrea M. DickeySteve SmithJason G. KerkvlietJustin W. TaraskaAdam D. HoppeNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Brandon L. Scott Kem A. Sochacki Shalini T. Low-Nam Elizabeth M. Bailey QuocAhn Luu Amy Hor Andrea M. Dickey Steve Smith Jason G. Kerkvliet Justin W. Taraska Adam D. Hoppe Membrane bending occurs at all stages of clathrin-coat assembly and defines endocytic dynamics
description	Two distinct and opposing models for clathrin-mediated endocytosis have been inferred from EM and structural biology data. Here the authors develop an optical method to directly visualize membrane-bending dynamics and show that coat assembly accommodates membrane bending during or after the assembly of the clathrin lattice, which is not predicted by either model.
format	article
author	Brandon L. Scott Kem A. Sochacki Shalini T. Low-Nam Elizabeth M. Bailey QuocAhn Luu Amy Hor Andrea M. Dickey Steve Smith Jason G. Kerkvliet Justin W. Taraska Adam D. Hoppe
author_facet	Brandon L. Scott Kem A. Sochacki Shalini T. Low-Nam Elizabeth M. Bailey QuocAhn Luu Amy Hor Andrea M. Dickey Steve Smith Jason G. Kerkvliet Justin W. Taraska Adam D. Hoppe
author_sort	Brandon L. Scott
title	Membrane bending occurs at all stages of clathrin-coat assembly and defines endocytic dynamics
title_short	Membrane bending occurs at all stages of clathrin-coat assembly and defines endocytic dynamics
title_full	Membrane bending occurs at all stages of clathrin-coat assembly and defines endocytic dynamics
title_fullStr	Membrane bending occurs at all stages of clathrin-coat assembly and defines endocytic dynamics
title_full_unstemmed	Membrane bending occurs at all stages of clathrin-coat assembly and defines endocytic dynamics
title_sort	membrane bending occurs at all stages of clathrin-coat assembly and defines endocytic dynamics
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/2fe8db89130d4f17aa027a673b9544f1
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Membrane bending occurs at all stages of clathrin-coat assembly and defines endocytic dynamics

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