Allosteric modulation of ghrelin receptor signaling by lipids

The membrane is an integral component of the G protein-coupled receptor signaling machinery. Here authors demonstrate that lipids regulate the signaling efficacy and selectivity of the ghrelin receptor GHSR through specific interactions and bulk effects and observe PIP2 and GM3 induced shifts of the...

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Bibliographic Details
Main Authors: Marjorie Damian, Maxime Louet, Antoniel Augusto Severo Gomes, Céline M’Kadmi, Séverine Denoyelle, Sonia Cantel, Sophie Mary, Paulo M. Bisch, Jean-Alain Fehrentz, Laurent J. Catoire, Nicolas Floquet, Jean-Louis Banères
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/2ff1774b14b842c1ba2707a2e704a84a
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