Allosteric modulation of ghrelin receptor signaling by lipids
The membrane is an integral component of the G protein-coupled receptor signaling machinery. Here authors demonstrate that lipids regulate the signaling efficacy and selectivity of the ghrelin receptor GHSR through specific interactions and bulk effects and observe PIP2 and GM3 induced shifts of the...
Enregistré dans:
Auteurs principaux: | Marjorie Damian, Maxime Louet, Antoniel Augusto Severo Gomes, Céline M’Kadmi, Séverine Denoyelle, Sonia Cantel, Sophie Mary, Paulo M. Bisch, Jean-Alain Fehrentz, Laurent J. Catoire, Nicolas Floquet, Jean-Louis Banères |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/2ff1774b14b842c1ba2707a2e704a84a |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Structural basis of human ghrelin receptor signaling by ghrelin and the synthetic agonist ibutamoren
par: Heng Liu, et autres
Publié: (2021) -
Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode
par: Yuki Shiimura, et autres
Publié: (2020) -
Mechanism of the inhibitory effect of ghrelin in sepsis
par: Asha Jacob, et autres
Publié: (2010) -
New Insights on the Relationship between Leptin, Ghrelin, and Leptin/Ghrelin Ratio Enforced by Body Mass Index in Obesity and Diabetes
par: Adela-Viviana Sitar-Tǎut, et autres
Publié: (2021) -
Effect of unacylated ghrelin on peripheral nerve regeneration
par: Giulia Ronchi, et autres
Publié: (2021)