Towards water-soluble [60]fullerenes for the delivery of siRNA in a prostate cancer model

Towards water-soluble [60]fullerenes for the delivery of siRNA in a prostate cancer model

Abstract This paper presents two water-soluble fullerene nanomaterials (HexakisaminoC60 and monoglucosamineC60, which is called here JK39) that were developed and synthesized as non-viral siRNA transfection nanosystems. The developed two-step Bingel–Hirsch reaction enables the chemical modification...

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Autores principales: Julia Korzuch, Monika Rak, Katarzyna Balin, Maciej Zubko, Olga Głowacka, Mateusz Dulski, Robert Musioł, Zbigniew Madeja, Maciej Serda
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/2ff5f227aeb34945a7460424bb027439
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