Circulating tumor cells in head and neck cancer: A review
Carcinoma of the head and neck represents 3.5% of all cancers, and the vast majority of these tumors are squamous cell carcinoma (HNSCC). With a stable overall survival rate of 50% among all stages, there is continued interested in developing measures for early detection and disease aggressiveness....
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KeAi Communications Co., Ltd.
2016
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oai:doaj.org-article:30166729645c4ffa95d41eafaa81dd192021-12-02T10:50:15ZCirculating tumor cells in head and neck cancer: A review2095-881110.1016/j.wjorl.2016.05.003https://doaj.org/article/30166729645c4ffa95d41eafaa81dd192016-06-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S209588111630021Xhttps://doaj.org/toc/2095-8811Carcinoma of the head and neck represents 3.5% of all cancers, and the vast majority of these tumors are squamous cell carcinoma (HNSCC). With a stable overall survival rate of 50% among all stages, there is continued interested in developing measures for early detection and disease aggressiveness. Circulating tumor cells (CTCs) have been identified as a potential marker for early metastatic disease, response to treatment, and surveillance in head and neck squamous cell carcinoma. In this article, techniques of CTC detection, applications of CTC technology, and outcomes of HNSCC patients will be discussed. Keywords: Circulating tumor cell, Metastasis, Head and neck cancer, Squamous cellKyle P. McMullenJeffrey J. ChalmersJas C. LangPawan KumarKris R. JatanaKeAi Communications Co., Ltd.articleOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 2, Iss 2, Pp 109-116 (2016) |
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Otorhinolaryngology RF1-547 Surgery RD1-811 |
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Otorhinolaryngology RF1-547 Surgery RD1-811 Kyle P. McMullen Jeffrey J. Chalmers Jas C. Lang Pawan Kumar Kris R. Jatana Circulating tumor cells in head and neck cancer: A review |
description |
Carcinoma of the head and neck represents 3.5% of all cancers, and the vast majority of these tumors are squamous cell carcinoma (HNSCC). With a stable overall survival rate of 50% among all stages, there is continued interested in developing measures for early detection and disease aggressiveness. Circulating tumor cells (CTCs) have been identified as a potential marker for early metastatic disease, response to treatment, and surveillance in head and neck squamous cell carcinoma. In this article, techniques of CTC detection, applications of CTC technology, and outcomes of HNSCC patients will be discussed. Keywords: Circulating tumor cell, Metastasis, Head and neck cancer, Squamous cell |
format |
article |
author |
Kyle P. McMullen Jeffrey J. Chalmers Jas C. Lang Pawan Kumar Kris R. Jatana |
author_facet |
Kyle P. McMullen Jeffrey J. Chalmers Jas C. Lang Pawan Kumar Kris R. Jatana |
author_sort |
Kyle P. McMullen |
title |
Circulating tumor cells in head and neck cancer: A review |
title_short |
Circulating tumor cells in head and neck cancer: A review |
title_full |
Circulating tumor cells in head and neck cancer: A review |
title_fullStr |
Circulating tumor cells in head and neck cancer: A review |
title_full_unstemmed |
Circulating tumor cells in head and neck cancer: A review |
title_sort |
circulating tumor cells in head and neck cancer: a review |
publisher |
KeAi Communications Co., Ltd. |
publishDate |
2016 |
url |
https://doaj.org/article/30166729645c4ffa95d41eafaa81dd19 |
work_keys_str_mv |
AT kylepmcmullen circulatingtumorcellsinheadandneckcancerareview AT jeffreyjchalmers circulatingtumorcellsinheadandneckcancerareview AT jasclang circulatingtumorcellsinheadandneckcancerareview AT pawankumar circulatingtumorcellsinheadandneckcancerareview AT krisrjatana circulatingtumorcellsinheadandneckcancerareview |
_version_ |
1718396580199923712 |