Circulating tumor cells in head and neck cancer: A review

Carcinoma of the head and neck represents 3.5% of all cancers, and the vast majority of these tumors are squamous cell carcinoma (HNSCC). With a stable overall survival rate of 50% among all stages, there is continued interested in developing measures for early detection and disease aggressiveness....

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Autores principales: Kyle P. McMullen, Jeffrey J. Chalmers, Jas C. Lang, Pawan Kumar, Kris R. Jatana
Formato: article
Lenguaje:EN
Publicado: KeAi Communications Co., Ltd. 2016
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Acceso en línea:https://doaj.org/article/30166729645c4ffa95d41eafaa81dd19
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spelling oai:doaj.org-article:30166729645c4ffa95d41eafaa81dd192021-12-02T10:50:15ZCirculating tumor cells in head and neck cancer: A review2095-881110.1016/j.wjorl.2016.05.003https://doaj.org/article/30166729645c4ffa95d41eafaa81dd192016-06-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S209588111630021Xhttps://doaj.org/toc/2095-8811Carcinoma of the head and neck represents 3.5% of all cancers, and the vast majority of these tumors are squamous cell carcinoma (HNSCC). With a stable overall survival rate of 50% among all stages, there is continued interested in developing measures for early detection and disease aggressiveness. Circulating tumor cells (CTCs) have been identified as a potential marker for early metastatic disease, response to treatment, and surveillance in head and neck squamous cell carcinoma. In this article, techniques of CTC detection, applications of CTC technology, and outcomes of HNSCC patients will be discussed. Keywords: Circulating tumor cell, Metastasis, Head and neck cancer, Squamous cellKyle P. McMullenJeffrey J. ChalmersJas C. LangPawan KumarKris R. JatanaKeAi Communications Co., Ltd.articleOtorhinolaryngologyRF1-547SurgeryRD1-811ENWorld Journal of Otorhinolaryngology-Head and Neck Surgery, Vol 2, Iss 2, Pp 109-116 (2016)
institution DOAJ
collection DOAJ
language EN
topic Otorhinolaryngology
RF1-547
Surgery
RD1-811
spellingShingle Otorhinolaryngology
RF1-547
Surgery
RD1-811
Kyle P. McMullen
Jeffrey J. Chalmers
Jas C. Lang
Pawan Kumar
Kris R. Jatana
Circulating tumor cells in head and neck cancer: A review
description Carcinoma of the head and neck represents 3.5% of all cancers, and the vast majority of these tumors are squamous cell carcinoma (HNSCC). With a stable overall survival rate of 50% among all stages, there is continued interested in developing measures for early detection and disease aggressiveness. Circulating tumor cells (CTCs) have been identified as a potential marker for early metastatic disease, response to treatment, and surveillance in head and neck squamous cell carcinoma. In this article, techniques of CTC detection, applications of CTC technology, and outcomes of HNSCC patients will be discussed. Keywords: Circulating tumor cell, Metastasis, Head and neck cancer, Squamous cell
format article
author Kyle P. McMullen
Jeffrey J. Chalmers
Jas C. Lang
Pawan Kumar
Kris R. Jatana
author_facet Kyle P. McMullen
Jeffrey J. Chalmers
Jas C. Lang
Pawan Kumar
Kris R. Jatana
author_sort Kyle P. McMullen
title Circulating tumor cells in head and neck cancer: A review
title_short Circulating tumor cells in head and neck cancer: A review
title_full Circulating tumor cells in head and neck cancer: A review
title_fullStr Circulating tumor cells in head and neck cancer: A review
title_full_unstemmed Circulating tumor cells in head and neck cancer: A review
title_sort circulating tumor cells in head and neck cancer: a review
publisher KeAi Communications Co., Ltd.
publishDate 2016
url https://doaj.org/article/30166729645c4ffa95d41eafaa81dd19
work_keys_str_mv AT kylepmcmullen circulatingtumorcellsinheadandneckcancerareview
AT jeffreyjchalmers circulatingtumorcellsinheadandneckcancerareview
AT jasclang circulatingtumorcellsinheadandneckcancerareview
AT pawankumar circulatingtumorcellsinheadandneckcancerareview
AT krisrjatana circulatingtumorcellsinheadandneckcancerareview
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