Structural characterisation of the nuclear import receptor importin alpha in complex with the bipartite NLS of Prp20.

The translocation of macromolecules into the nucleus is a fundamental eukaryotic process, regulating gene expression, cell division and differentiation, but which is impaired in a range of significant diseases including cancer and viral infection. The import of proteins into the nucleus is generally...

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Bibliographic Details
Main Authors: Noelia Roman, Mary Christie, Crystall M D Swarbrick, Bostjan Kobe, Jade K Forwood
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/3029e82fd2e9428a8402e883fde5c545
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