Prophylaxis of migraine: general principles and patient acceptance

Domenico D&rsquo;Amico1, Stewart J Tepper21Headache Center, Department of Neurological Sciences, C Besta Neurological Institute, Milan, Italy; 2Center for Headache and Pain, Neurological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USAAbstract: Migraine is a chronic neurological...

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Autores principales:	Domenico D&rsquo;Amico, Stewart J Tepper
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/302c3975e96e49e78b2b05ac1639dbc0
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spelling	oai:doaj.org-article:302c3975e96e49e78b2b05ac1639dbc02021-12-02T01:21:09ZProphylaxis of migraine: general principles and patient acceptance1176-63281178-2021https://doaj.org/article/302c3975e96e49e78b2b05ac1639dbc02008-12-01T00:00:00Zhttp://www.dovepress.com/prophylaxis-of-migraine-general-principles-and-patient-acceptance-a2756https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Domenico D&rsquo;Amico1, Stewart J Tepper21Headache Center, Department of Neurological Sciences, C Besta Neurological Institute, Milan, Italy; 2Center for Headache and Pain, Neurological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USAAbstract: Migraine is a chronic neurological condition with episodic exacerbations. Migraine is highly prevalent, and associated with significant pain, disability, and diminished quality of life. Migraine management is an important health care issue. Migraine management includes avoidance of trigger factors, lifestyle modifications, non-pharmacological therapies, and medications. Pharmacological treatment is traditionally divided into acute or symptomatic treatment, and preventive treatment or prophylaxis. Many migraine patients can be treated using only acute treatment. Patients with severe and/or frequent migraines require long-term preventive therapy. Prophylaxis requires daily administration of anti-migraine compounds with potential adverse events or contraindications, and may also interfere with other concurrent conditions and treatments. These problems may induce patients to reject the idea of a preventive treatment, leading to poor patient adherence. This paper reviews the main factors influencing patient acceptance of anti-migraine prophylaxis, providing practical suggestions to enhance patient willingness to accept pharmacological anti-migraine preventive therapy. We also provide information about the main clinical characteristics of migraine, and their negative consequences. The circumstances warranting prophylaxis in migraine patients as well as the main characteristics of the compounds currently used in migraine prophylaxis will also be briefly discussed, focusing on those aspects which can enhance patient acceptance and adherence.Keywords: migraine, prophylaxis, preventive therapy, acceptance, adherence Domenico D&rsquo;AmicoStewart J TepperDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2008, Iss Issue 6, Pp 1155-1167 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Domenico D&rsquo;Amico Stewart J Tepper Prophylaxis of migraine: general principles and patient acceptance
description	Domenico D&rsquo;Amico1, Stewart J Tepper21Headache Center, Department of Neurological Sciences, C Besta Neurological Institute, Milan, Italy; 2Center for Headache and Pain, Neurological Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USAAbstract: Migraine is a chronic neurological condition with episodic exacerbations. Migraine is highly prevalent, and associated with significant pain, disability, and diminished quality of life. Migraine management is an important health care issue. Migraine management includes avoidance of trigger factors, lifestyle modifications, non-pharmacological therapies, and medications. Pharmacological treatment is traditionally divided into acute or symptomatic treatment, and preventive treatment or prophylaxis. Many migraine patients can be treated using only acute treatment. Patients with severe and/or frequent migraines require long-term preventive therapy. Prophylaxis requires daily administration of anti-migraine compounds with potential adverse events or contraindications, and may also interfere with other concurrent conditions and treatments. These problems may induce patients to reject the idea of a preventive treatment, leading to poor patient adherence. This paper reviews the main factors influencing patient acceptance of anti-migraine prophylaxis, providing practical suggestions to enhance patient willingness to accept pharmacological anti-migraine preventive therapy. We also provide information about the main clinical characteristics of migraine, and their negative consequences. The circumstances warranting prophylaxis in migraine patients as well as the main characteristics of the compounds currently used in migraine prophylaxis will also be briefly discussed, focusing on those aspects which can enhance patient acceptance and adherence.Keywords: migraine, prophylaxis, preventive therapy, acceptance, adherence
format	article
author	Domenico D&rsquo;Amico Stewart J Tepper
author_facet	Domenico D&rsquo;Amico Stewart J Tepper
author_sort	Domenico D&rsquo;Amico
title	Prophylaxis of migraine: general principles and patient acceptance
title_short	Prophylaxis of migraine: general principles and patient acceptance
title_full	Prophylaxis of migraine: general principles and patient acceptance
title_fullStr	Prophylaxis of migraine: general principles and patient acceptance
title_full_unstemmed	Prophylaxis of migraine: general principles and patient acceptance
title_sort	prophylaxis of migraine: general principles and patient acceptance
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/302c3975e96e49e78b2b05ac1639dbc0
work_keys_str_mv	AT domenicodamprsquoamico prophylaxisofmigrainegeneralprinciplesandpatientacceptance AT stewartjtepper prophylaxisofmigrainegeneralprinciplesandpatientacceptance
_version_	1718403130974011392

Prophylaxis of migraine: general principles and patient acceptance

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