Analyses in zebrafish embryos reveal that nanotoxicity profiles are dependent on surface-functionalization controlled penetrance of biological membranes

Abstract Mesoporous silica nanoparticles (MSNs) are extensively explored as drug delivery systems, but in depth understanding of design-toxicity relationships is still scarce. We used zebrafish (Danio rerio) embryos to study toxicity profiles of differently surface functionalized MSNs. Embryos with...

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Bibliographic Details
Main Authors: Ilkka Paatero, Eudald Casals, Rasmus Niemi, Ezgi Özliseli, Jessica M. Rosenholm, Cecilia Sahlgren
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/3030e357a6c242d8a8ea19a59c6cc4bc
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