Synthesis, characterization, and mechanistic studies of a gold nanoparticle–amphotericin B covalent conjugate with enhanced antileishmanial efficacy and reduced cytotoxicity

Synthesis, characterization, and mechanistic studies of a gold nanoparticle–amphotericin B covalent conjugate with enhanced antileishmanial efficacy and reduced cytotoxicity

Prakash Kumar,1 Pushkar Shivam,*,2 Saptarshi Mandal,*,3 Pragya Prasanna,1 Saurabh Kumar,1 Surendra Rajit Prasad,1 Ashish Kumar,4 Prolay Das,3 Vahab Ali,5 Shubhankar Kumar Singh,2 Debabrata Mandal11Department of Biotechnology, National Institute of Pharmaceutical Education and Research (NIPER) &n...

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Autores principales: Kumar P, Shivam P, Mandal S, Prasanna P, Kumar S, Prasad SR, Kumar A, Das P, Ali V, Singh SK, Mandal D
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2019
Materias:
gold nanoparticle
Amphotericin B
antileishmanial
macrophage uptake
ergosterol
immunostimulator
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/303109f71b1a4ab28a430db566d3a540
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