The regulate function of polysaccharides and oligosaccharides that with sulfate group on immune-related disease

Sulfate polysaccharide is a kind of polyanionic linear macromolecular compound which contained sulfate groups. In vivo, most of them combine with proteins to form proteoglycans. The oligosaccharides obtained by degradation from polysaccharides would have different biological activities. Sulfate poly...

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Autores principales:	Ling Xu, Dan He, Changlin Zhang, Ying Bai, Cuili Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Sulfated polysaccharide Sulfated oligosaccharide Biological activity Immunity Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/30314b9ed6dc4ce09461d8105a378057
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spelling	oai:doaj.org-article:30314b9ed6dc4ce09461d8105a3780572021-12-02T05:00:16ZThe regulate function of polysaccharides and oligosaccharides that with sulfate group on immune-related disease1756-464610.1016/j.jff.2021.104870https://doaj.org/article/30314b9ed6dc4ce09461d8105a3780572022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1756464621005193https://doaj.org/toc/1756-4646Sulfate polysaccharide is a kind of polyanionic linear macromolecular compound which contained sulfate groups. In vivo, most of them combine with proteins to form proteoglycans. The oligosaccharides obtained by degradation from polysaccharides would have different biological activities. Sulfate polysaccharides and oligosaccharides have immunomodulatory activity, which can be involved in activating immune cell recognition, controlling immune cell activity and reducing the side effects caused by inflammatory reactions. Polysaccharides treated with sulfate can act on multiple targets of the immune systems, affecting the occurrence and development of diseases and even cancer. In this article, polysaccharide and oligosaccharide containing sulfate groups were classified as endogenous and exogenous, and sulfated derivatives. And their biological activities in immune regulation were reviewed. Polysaccharides and oligosaccharides or the derivatives after sulfuric acid modification would have relatively unique biological activities due to the negative charge of the sulfate group and the change of their solubility.Ling XuDan HeChanglin ZhangYing BaiCuili ZhangElsevierarticleSulfated polysaccharideSulfated oligosaccharideBiological activityImmunityNutrition. Foods and food supplyTX341-641ENJournal of Functional Foods, Vol 88, Iss , Pp 104870- (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Sulfated polysaccharide Sulfated oligosaccharide Biological activity Immunity Nutrition. Foods and food supply TX341-641
spellingShingle	Sulfated polysaccharide Sulfated oligosaccharide Biological activity Immunity Nutrition. Foods and food supply TX341-641 Ling Xu Dan He Changlin Zhang Ying Bai Cuili Zhang The regulate function of polysaccharides and oligosaccharides that with sulfate group on immune-related disease
description	Sulfate polysaccharide is a kind of polyanionic linear macromolecular compound which contained sulfate groups. In vivo, most of them combine with proteins to form proteoglycans. The oligosaccharides obtained by degradation from polysaccharides would have different biological activities. Sulfate polysaccharides and oligosaccharides have immunomodulatory activity, which can be involved in activating immune cell recognition, controlling immune cell activity and reducing the side effects caused by inflammatory reactions. Polysaccharides treated with sulfate can act on multiple targets of the immune systems, affecting the occurrence and development of diseases and even cancer. In this article, polysaccharide and oligosaccharide containing sulfate groups were classified as endogenous and exogenous, and sulfated derivatives. And their biological activities in immune regulation were reviewed. Polysaccharides and oligosaccharides or the derivatives after sulfuric acid modification would have relatively unique biological activities due to the negative charge of the sulfate group and the change of their solubility.
format	article
author	Ling Xu Dan He Changlin Zhang Ying Bai Cuili Zhang
author_facet	Ling Xu Dan He Changlin Zhang Ying Bai Cuili Zhang
author_sort	Ling Xu
title	The regulate function of polysaccharides and oligosaccharides that with sulfate group on immune-related disease
title_short	The regulate function of polysaccharides and oligosaccharides that with sulfate group on immune-related disease
title_full	The regulate function of polysaccharides and oligosaccharides that with sulfate group on immune-related disease
title_fullStr	The regulate function of polysaccharides and oligosaccharides that with sulfate group on immune-related disease
title_full_unstemmed	The regulate function of polysaccharides and oligosaccharides that with sulfate group on immune-related disease
title_sort	regulate function of polysaccharides and oligosaccharides that with sulfate group on immune-related disease
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/30314b9ed6dc4ce09461d8105a378057
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The regulate function of polysaccharides and oligosaccharides that with sulfate group on immune-related disease

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