Molecular basis of dimer formation during the biosynthesis of benzofluorene-containing atypical angucyclines

Molecular basis of dimer formation during the biosynthesis of benzofluorene-containing atypical angucyclines

Benzofluorene-containing angucyclines, bacterial natural compounds with potential use as therapeutics/antibiotics, occur as dimers. Here, the authors elucidated the dimerization mechanism which turned out to work spontaneously, without enzymatic catalysis.

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Detalles Bibliográficos
Autores principales: Chunshuai Huang, Chunfang Yang, Wenjun Zhang, Liping Zhang, Bidhan Chandra De, Yiguang Zhu, Xiaodong Jiang, Chunyan Fang, Qingbo Zhang, Cheng-Shan Yuan, Hung-wen Liu, Changsheng Zhang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
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Acceso en línea:https://doaj.org/article/30344ff8e3c44b39b61e7fdaf8585390
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