Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man

Kathir Yoganathan1, Michael Austin21Department of Genito-Urinary Medicine, 2Department of Ophthalmology, Singleton Hospital, Sketty, Swansea, SA2 8QA, UKAbstract: Opportunistic cytomegalovirus (CMV) infection is common in severely immunocompromised HIV-positive patients. The retina is the commonest...

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Autores principales: Kathir Yoganathan, Michael Austin
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Publicado: Dove Medical Press 2008
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spelling oai:doaj.org-article:303655579d3c49ba9eaeb9f81d53db5d2021-12-02T09:10:19ZIschemic maculopathy in zidovudine-induced anemia in an HIV-positive man1177-54671177-5483https://doaj.org/article/303655579d3c49ba9eaeb9f81d53db5d2008-03-01T00:00:00Zhttp://www.dovepress.com/ischemic-maculopathy-in-zidovudine-induced-anemia-in-an-hiv-positive-m-a344https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Kathir Yoganathan1, Michael Austin21Department of Genito-Urinary Medicine, 2Department of Ophthalmology, Singleton Hospital, Sketty, Swansea, SA2 8QA, UKAbstract: Opportunistic cytomegalovirus (CMV) infection is common in severely immunocompromised HIV-positive patients. The retina is the commonest site of involvement with hemorrhages a prominent feature. CMV retinitis affects 40% of HIV positive patients who have CD4 count of less than 100 cell/mm3, and in these circumstances clinicians are likely to consider commencing anti-CMV therapy without considering other causes. We report a man with HIV who developed bilateral retinal hemorrhages and ischemic maculopathy in association with zidovudine (AZT)-induced anemia. Retinal hemorrhages resolved following blood transfusion.Keywords: Ischemic maculopathy, retinal hemorrhages, anemia, zidovudine, HIV Kathir YoganathanMichael AustinDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2008, Iss Issue 1, Pp 237-239 (2008)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Kathir Yoganathan
Michael Austin
Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
description Kathir Yoganathan1, Michael Austin21Department of Genito-Urinary Medicine, 2Department of Ophthalmology, Singleton Hospital, Sketty, Swansea, SA2 8QA, UKAbstract: Opportunistic cytomegalovirus (CMV) infection is common in severely immunocompromised HIV-positive patients. The retina is the commonest site of involvement with hemorrhages a prominent feature. CMV retinitis affects 40% of HIV positive patients who have CD4 count of less than 100 cell/mm3, and in these circumstances clinicians are likely to consider commencing anti-CMV therapy without considering other causes. We report a man with HIV who developed bilateral retinal hemorrhages and ischemic maculopathy in association with zidovudine (AZT)-induced anemia. Retinal hemorrhages resolved following blood transfusion.Keywords: Ischemic maculopathy, retinal hemorrhages, anemia, zidovudine, HIV
format article
author Kathir Yoganathan
Michael Austin
author_facet Kathir Yoganathan
Michael Austin
author_sort Kathir Yoganathan
title Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
title_short Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
title_full Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
title_fullStr Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
title_full_unstemmed Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
title_sort ischemic maculopathy in zidovudine-induced anemia in an hiv-positive man
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/303655579d3c49ba9eaeb9f81d53db5d
work_keys_str_mv AT kathiryoganathan ischemicmaculopathyinzidovudineinducedanemiainanhivpositiveman
AT michaelaustin ischemicmaculopathyinzidovudineinducedanemiainanhivpositiveman
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