Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man
Kathir Yoganathan1, Michael Austin21Department of Genito-Urinary Medicine, 2Department of Ophthalmology, Singleton Hospital, Sketty, Swansea, SA2 8QA, UKAbstract: Opportunistic cytomegalovirus (CMV) infection is common in severely immunocompromised HIV-positive patients. The retina is the commonest...
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Dove Medical Press
2008
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oai:doaj.org-article:303655579d3c49ba9eaeb9f81d53db5d2021-12-02T09:10:19ZIschemic maculopathy in zidovudine-induced anemia in an HIV-positive man1177-54671177-5483https://doaj.org/article/303655579d3c49ba9eaeb9f81d53db5d2008-03-01T00:00:00Zhttp://www.dovepress.com/ischemic-maculopathy-in-zidovudine-induced-anemia-in-an-hiv-positive-m-a344https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Kathir Yoganathan1, Michael Austin21Department of Genito-Urinary Medicine, 2Department of Ophthalmology, Singleton Hospital, Sketty, Swansea, SA2 8QA, UKAbstract: Opportunistic cytomegalovirus (CMV) infection is common in severely immunocompromised HIV-positive patients. The retina is the commonest site of involvement with hemorrhages a prominent feature. CMV retinitis affects 40% of HIV positive patients who have CD4 count of less than 100 cell/mm3, and in these circumstances clinicians are likely to consider commencing anti-CMV therapy without considering other causes. We report a man with HIV who developed bilateral retinal hemorrhages and ischemic maculopathy in association with zidovudine (AZT)-induced anemia. Retinal hemorrhages resolved following blood transfusion.Keywords: Ischemic maculopathy, retinal hemorrhages, anemia, zidovudine, HIV Kathir YoganathanMichael AustinDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2008, Iss Issue 1, Pp 237-239 (2008) |
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Ophthalmology RE1-994 Kathir Yoganathan Michael Austin Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man |
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Kathir Yoganathan1, Michael Austin21Department of Genito-Urinary Medicine, 2Department of Ophthalmology, Singleton Hospital, Sketty, Swansea, SA2 8QA, UKAbstract: Opportunistic cytomegalovirus (CMV) infection is common in severely immunocompromised HIV-positive patients. The retina is the commonest site of involvement with hemorrhages a prominent feature. CMV retinitis affects 40% of HIV positive patients who have CD4 count of less than 100 cell/mm3, and in these circumstances clinicians are likely to consider commencing anti-CMV therapy without considering other causes. We report a man with HIV who developed bilateral retinal hemorrhages and ischemic maculopathy in association with zidovudine (AZT)-induced anemia. Retinal hemorrhages resolved following blood transfusion.Keywords: Ischemic maculopathy, retinal hemorrhages, anemia, zidovudine, HIV |
format |
article |
author |
Kathir Yoganathan Michael Austin |
author_facet |
Kathir Yoganathan Michael Austin |
author_sort |
Kathir Yoganathan |
title |
Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man |
title_short |
Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man |
title_full |
Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man |
title_fullStr |
Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man |
title_full_unstemmed |
Ischemic maculopathy in zidovudine-induced anemia in an HIV-positive man |
title_sort |
ischemic maculopathy in zidovudine-induced anemia in an hiv-positive man |
publisher |
Dove Medical Press |
publishDate |
2008 |
url |
https://doaj.org/article/303655579d3c49ba9eaeb9f81d53db5d |
work_keys_str_mv |
AT kathiryoganathan ischemicmaculopathyinzidovudineinducedanemiainanhivpositiveman AT michaelaustin ischemicmaculopathyinzidovudineinducedanemiainanhivpositiveman |
_version_ |
1718398176454508544 |