Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor

Involved in various diseases, hyaluronic acid is an important indicator of pathophysiology. Here, the authors report on a solid-state nanopore for the detection of the molecular weight and abundance of hyaluronic acid and demonstrate the system by studying an equine model of osteoarthritis

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Auteurs principaux: Felipe Rivas, Osama K. Zahid, Heidi L. Reesink, Bridgette T. Peal, Alan J. Nixon, Paul L. DeAngelis, Aleksander Skardal, Elaheh Rahbar, Adam R. Hall
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Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/304b9e3831cb41d6b8fc10f8c203cd74
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spelling oai:doaj.org-article:304b9e3831cb41d6b8fc10f8c203cd742021-12-02T15:34:39ZLabel-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor10.1038/s41467-018-03439-x2041-1723https://doaj.org/article/304b9e3831cb41d6b8fc10f8c203cd742018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03439-xhttps://doaj.org/toc/2041-1723Involved in various diseases, hyaluronic acid is an important indicator of pathophysiology. Here, the authors report on a solid-state nanopore for the detection of the molecular weight and abundance of hyaluronic acid and demonstrate the system by studying an equine model of osteoarthritisFelipe RivasOsama K. ZahidHeidi L. ReesinkBridgette T. PealAlan J. NixonPaul L. DeAngelisAleksander SkardalElaheh RahbarAdam R. HallNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Felipe Rivas
Osama K. Zahid
Heidi L. Reesink
Bridgette T. Peal
Alan J. Nixon
Paul L. DeAngelis
Aleksander Skardal
Elaheh Rahbar
Adam R. Hall
Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
description Involved in various diseases, hyaluronic acid is an important indicator of pathophysiology. Here, the authors report on a solid-state nanopore for the detection of the molecular weight and abundance of hyaluronic acid and demonstrate the system by studying an equine model of osteoarthritis
format article
author Felipe Rivas
Osama K. Zahid
Heidi L. Reesink
Bridgette T. Peal
Alan J. Nixon
Paul L. DeAngelis
Aleksander Skardal
Elaheh Rahbar
Adam R. Hall
author_facet Felipe Rivas
Osama K. Zahid
Heidi L. Reesink
Bridgette T. Peal
Alan J. Nixon
Paul L. DeAngelis
Aleksander Skardal
Elaheh Rahbar
Adam R. Hall
author_sort Felipe Rivas
title Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
title_short Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
title_full Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
title_fullStr Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
title_full_unstemmed Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
title_sort label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/304b9e3831cb41d6b8fc10f8c203cd74
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