Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor

Involved in various diseases, hyaluronic acid is an important indicator of pathophysiology. Here, the authors report on a solid-state nanopore for the detection of the molecular weight and abundance of hyaluronic acid and demonstrate the system by studying an equine model of osteoarthritis

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Autores principales:	Felipe Rivas, Osama K. Zahid, Heidi L. Reesink, Bridgette T. Peal, Alan J. Nixon, Paul L. DeAngelis, Aleksander Skardal, Elaheh Rahbar, Adam R. Hall
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/304b9e3831cb41d6b8fc10f8c203cd74
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spelling	oai:doaj.org-article:304b9e3831cb41d6b8fc10f8c203cd742021-12-02T15:34:39ZLabel-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor10.1038/s41467-018-03439-x2041-1723https://doaj.org/article/304b9e3831cb41d6b8fc10f8c203cd742018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03439-xhttps://doaj.org/toc/2041-1723Involved in various diseases, hyaluronic acid is an important indicator of pathophysiology. Here, the authors report on a solid-state nanopore for the detection of the molecular weight and abundance of hyaluronic acid and demonstrate the system by studying an equine model of osteoarthritisFelipe RivasOsama K. ZahidHeidi L. ReesinkBridgette T. PealAlan J. NixonPaul L. DeAngelisAleksander SkardalElaheh RahbarAdam R. HallNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Felipe Rivas Osama K. Zahid Heidi L. Reesink Bridgette T. Peal Alan J. Nixon Paul L. DeAngelis Aleksander Skardal Elaheh Rahbar Adam R. Hall Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
description	Involved in various diseases, hyaluronic acid is an important indicator of pathophysiology. Here, the authors report on a solid-state nanopore for the detection of the molecular weight and abundance of hyaluronic acid and demonstrate the system by studying an equine model of osteoarthritis
format	article
author	Felipe Rivas Osama K. Zahid Heidi L. Reesink Bridgette T. Peal Alan J. Nixon Paul L. DeAngelis Aleksander Skardal Elaheh Rahbar Adam R. Hall
author_facet	Felipe Rivas Osama K. Zahid Heidi L. Reesink Bridgette T. Peal Alan J. Nixon Paul L. DeAngelis Aleksander Skardal Elaheh Rahbar Adam R. Hall
author_sort	Felipe Rivas
title	Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
title_short	Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
title_full	Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
title_fullStr	Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
title_full_unstemmed	Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
title_sort	label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/304b9e3831cb41d6b8fc10f8c203cd74
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Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor

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