Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor
Involved in various diseases, hyaluronic acid is an important indicator of pathophysiology. Here, the authors report on a solid-state nanopore for the detection of the molecular weight and abundance of hyaluronic acid and demonstrate the system by studying an equine model of osteoarthritis
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2018
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oai:doaj.org-article:304b9e3831cb41d6b8fc10f8c203cd742021-12-02T15:34:39ZLabel-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor10.1038/s41467-018-03439-x2041-1723https://doaj.org/article/304b9e3831cb41d6b8fc10f8c203cd742018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03439-xhttps://doaj.org/toc/2041-1723Involved in various diseases, hyaluronic acid is an important indicator of pathophysiology. Here, the authors report on a solid-state nanopore for the detection of the molecular weight and abundance of hyaluronic acid and demonstrate the system by studying an equine model of osteoarthritisFelipe RivasOsama K. ZahidHeidi L. ReesinkBridgette T. PealAlan J. NixonPaul L. DeAngelisAleksander SkardalElaheh RahbarAdam R. HallNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018) |
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Science Q Felipe Rivas Osama K. Zahid Heidi L. Reesink Bridgette T. Peal Alan J. Nixon Paul L. DeAngelis Aleksander Skardal Elaheh Rahbar Adam R. Hall Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor |
description |
Involved in various diseases, hyaluronic acid is an important indicator of pathophysiology. Here, the authors report on a solid-state nanopore for the detection of the molecular weight and abundance of hyaluronic acid and demonstrate the system by studying an equine model of osteoarthritis |
format |
article |
author |
Felipe Rivas Osama K. Zahid Heidi L. Reesink Bridgette T. Peal Alan J. Nixon Paul L. DeAngelis Aleksander Skardal Elaheh Rahbar Adam R. Hall |
author_facet |
Felipe Rivas Osama K. Zahid Heidi L. Reesink Bridgette T. Peal Alan J. Nixon Paul L. DeAngelis Aleksander Skardal Elaheh Rahbar Adam R. Hall |
author_sort |
Felipe Rivas |
title |
Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor |
title_short |
Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor |
title_full |
Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor |
title_fullStr |
Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor |
title_full_unstemmed |
Label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor |
title_sort |
label-free analysis of physiological hyaluronan size distribution with a solid-state nanopore sensor |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/304b9e3831cb41d6b8fc10f8c203cd74 |
work_keys_str_mv |
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