Effects of the Manufacturing Methods on the Mechanical Properties of a Medical-Grade Copolymer Poly(L-lactide-co-D,L-lactide) and Poly(L-lactide-co-ε-caprolactone) Blend

Biocompatible and biodegradable polymers represent the future in the manufacturing of medical implantable solutions. As of today, these are generally manufactured with metallic components which cannot be naturally absorbed within the human body. This requires performing an additional surgical proced...

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Autores principales:	Mariana Rodriguez Reinoso, Marco Civera, Vito Burgio, Annalisa Chiappone, Oliver Grimaldo Ruiz, Alessandra D’Anna, Carmela Riccio, Ignazio Roppolo, Alberto Frache, Paola Antonaci, Cecilia Surace
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	biodegradable polymer lactide caprolactone injection and compression molding mechanical properties Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85
Acceso en línea:	https://doaj.org/article/30591da00ccd40cf9a07a3baf3c9de42
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spelling	oai:doaj.org-article:30591da00ccd40cf9a07a3baf3c9de422021-11-11T17:57:18ZEffects of the Manufacturing Methods on the Mechanical Properties of a Medical-Grade Copolymer Poly(L-lactide-co-D,L-lactide) and Poly(L-lactide-co-ε-caprolactone) Blend10.3390/ma142163811996-1944https://doaj.org/article/30591da00ccd40cf9a07a3baf3c9de422021-10-01T00:00:00Zhttps://www.mdpi.com/1996-1944/14/21/6381https://doaj.org/toc/1996-1944Biocompatible and biodegradable polymers represent the future in the manufacturing of medical implantable solutions. As of today, these are generally manufactured with metallic components which cannot be naturally absorbed within the human body. This requires performing an additional surgical procedure to remove the remnants after complete rehabilitation or to leave the devices in situ indefinitely. Nevertheless, the biomaterials used for this purpose must satisfy well-defined mechanical requirements. These are difficult to ascertain at the design phase since they depend not only on their physicochemical properties but also on the specific manufacturing methods used for the target application. Therefore, this research was focused on establishing the effects of the manufacturing methods on both the mechanical properties and the thermal behavior of a medical-grade copolymer blend. Specifically, Injection and Compression Molding were considered. A Poly(L-lactide-co-D,L-lactide)/Poly(L-lactide-co-ε-caprolactone) blend was considered for this investigation, with a ratio of 50/50 (<i>w/w</i>), aimed at the manufacturing of implantable devices for tendon repair. Interesting results were obtained.Mariana Rodriguez ReinosoMarco CiveraVito BurgioAnnalisa ChiapponeOliver Grimaldo RuizAlessandra D’AnnaCarmela RiccioIgnazio RoppoloAlberto FrachePaola AntonaciCecilia SuraceMDPI AGarticlebiodegradablepolymerlactidecaprolactoneinjection and compression moldingmechanical propertiesTechnologyTElectrical engineering. Electronics. Nuclear engineeringTK1-9971Engineering (General). Civil engineering (General)TA1-2040MicroscopyQH201-278.5Descriptive and experimental mechanicsQC120-168.85ENMaterials, Vol 14, Iss 6381, p 6381 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	biodegradable polymer lactide caprolactone injection and compression molding mechanical properties Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85
spellingShingle	biodegradable polymer lactide caprolactone injection and compression molding mechanical properties Technology T Electrical engineering. Electronics. Nuclear engineering TK1-9971 Engineering (General). Civil engineering (General) TA1-2040 Microscopy QH201-278.5 Descriptive and experimental mechanics QC120-168.85 Mariana Rodriguez Reinoso Marco Civera Vito Burgio Annalisa Chiappone Oliver Grimaldo Ruiz Alessandra D’Anna Carmela Riccio Ignazio Roppolo Alberto Frache Paola Antonaci Cecilia Surace Effects of the Manufacturing Methods on the Mechanical Properties of a Medical-Grade Copolymer Poly(L-lactide-co-D,L-lactide) and Poly(L-lactide-co-ε-caprolactone) Blend
description	Biocompatible and biodegradable polymers represent the future in the manufacturing of medical implantable solutions. As of today, these are generally manufactured with metallic components which cannot be naturally absorbed within the human body. This requires performing an additional surgical procedure to remove the remnants after complete rehabilitation or to leave the devices in situ indefinitely. Nevertheless, the biomaterials used for this purpose must satisfy well-defined mechanical requirements. These are difficult to ascertain at the design phase since they depend not only on their physicochemical properties but also on the specific manufacturing methods used for the target application. Therefore, this research was focused on establishing the effects of the manufacturing methods on both the mechanical properties and the thermal behavior of a medical-grade copolymer blend. Specifically, Injection and Compression Molding were considered. A Poly(L-lactide-co-D,L-lactide)/Poly(L-lactide-co-ε-caprolactone) blend was considered for this investigation, with a ratio of 50/50 (<i>w/w</i>), aimed at the manufacturing of implantable devices for tendon repair. Interesting results were obtained.
format	article
author	Mariana Rodriguez Reinoso Marco Civera Vito Burgio Annalisa Chiappone Oliver Grimaldo Ruiz Alessandra D’Anna Carmela Riccio Ignazio Roppolo Alberto Frache Paola Antonaci Cecilia Surace
author_facet	Mariana Rodriguez Reinoso Marco Civera Vito Burgio Annalisa Chiappone Oliver Grimaldo Ruiz Alessandra D’Anna Carmela Riccio Ignazio Roppolo Alberto Frache Paola Antonaci Cecilia Surace
author_sort	Mariana Rodriguez Reinoso
title	Effects of the Manufacturing Methods on the Mechanical Properties of a Medical-Grade Copolymer Poly(L-lactide-co-D,L-lactide) and Poly(L-lactide-co-ε-caprolactone) Blend
title_short	Effects of the Manufacturing Methods on the Mechanical Properties of a Medical-Grade Copolymer Poly(L-lactide-co-D,L-lactide) and Poly(L-lactide-co-ε-caprolactone) Blend
title_full	Effects of the Manufacturing Methods on the Mechanical Properties of a Medical-Grade Copolymer Poly(L-lactide-co-D,L-lactide) and Poly(L-lactide-co-ε-caprolactone) Blend
title_fullStr	Effects of the Manufacturing Methods on the Mechanical Properties of a Medical-Grade Copolymer Poly(L-lactide-co-D,L-lactide) and Poly(L-lactide-co-ε-caprolactone) Blend
title_full_unstemmed	Effects of the Manufacturing Methods on the Mechanical Properties of a Medical-Grade Copolymer Poly(L-lactide-co-D,L-lactide) and Poly(L-lactide-co-ε-caprolactone) Blend
title_sort	effects of the manufacturing methods on the mechanical properties of a medical-grade copolymer poly(l-lactide-co-d,l-lactide) and poly(l-lactide-co-ε-caprolactone) blend
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/30591da00ccd40cf9a07a3baf3c9de42
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Effects of the Manufacturing Methods on the Mechanical Properties of a Medical-Grade Copolymer Poly(L-lactide-co-D,L-lactide) and Poly(L-lactide-co-ε-caprolactone) Blend

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