Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection.

Genetic and structural basis for selection of a ubiquitous T cell receptor deployed in Epstein-Barr virus infection.

Despite the ∼10(18) αβ T cell receptor (TCR) structures that can be randomly manufactured by the human thymus, some surface more frequently than others. The pinnacles of this distortion are public TCRs, which exhibit amino acid-identical structures across different individuals. Public TCRs are thoug...

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Detalles Bibliográficos
Autores principales: John J Miles, Anna M Bulek, David K Cole, Emma Gostick, Andrea J A Schauenburg, Garry Dolton, Vanessa Venturi, Miles P Davenport, Mai Ping Tan, Scott R Burrows, Linda Wooldridge, David A Price, Pierre J Rizkallah, Andrew K Sewell
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2010
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/306c4ef650b24c9d8ee4fe6f2fc17f93
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