Histiocytoid Sweet’s syndrome in a patient with myelodysplastic syndrome: report and review of the literature

The neutrophilic dermatoses are a group of disorders characterized by skin lesions for which histological examination reveals intense epidermal and/or dermal inflammatory infiltrates composed primarily of neutrophils without evidence of infection. The myelodysplastic syndromes consist of a heteroge...

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Autores principales: Michael M. Shalaby, Ryan R. Riahl, Les B. Rosen, Erik J. Soine
Formato: article
Lenguaje:EN
Publicado: Mattioli1885 2016
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Acceso en línea:https://doaj.org/article/307b9e9c3133420d87419748611f193c
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Sumario:The neutrophilic dermatoses are a group of disorders characterized by skin lesions for which histological examination reveals intense epidermal and/or dermal inflammatory infiltrates composed primarily of neutrophils without evidence of infection. The myelodysplastic syndromes consist of a heterogeneous group of malignant hematopoietic stem cell disorders characterized by dysplastic and inadequate blood cell production with a variable risk of transformation to acute leukemia. Rarely, histiocytoid Sweet’s syndrome occurring in patients with myelodysplastic syndrome has been described. We present a case of a 66-year-old woman with a history of myelodysplastic syndrome who developed histiocytoid Sweet’s syndrome. We also review the literature and characterize patients with myelodysplastic syndrome who have developed histiocytoid Sweet’s syndrome.