Sportmedizin im Wandel
Problem: Dyslipidaemia and physical inactivity are leading risk factors for the development of atherosclerotic disease, accounting annually for approximately 5.8 million deaths worldwide. A lipid-lowering effect of exercise is commonly assumed, but, in contrast to multi-modal lifestyle interventions...
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Dynamic Media Sales Verlag
2017
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oai:doaj.org-article:308553696cda4ae09b1a1e142dc7ade52021-11-16T19:01:41ZSportmedizin im Wandel0344-59252510-526410.5960/dzsm.2017.304https://doaj.org/article/308553696cda4ae09b1a1e142dc7ade52017-11-01T00:00:00Zhttps://www.germanjournalsportsmedicine.com/archive/archive-2017/heft-11/a-run-a-day-keeps-lipids-at-bay-regular-exercise-as-a-treatment-of-dyslipidaemias/https://doaj.org/toc/0344-5925https://doaj.org/toc/2510-5264Problem: Dyslipidaemia and physical inactivity are leading risk factors for the development of atherosclerotic disease, accounting annually for approximately 5.8 million deaths worldwide. A lipid-lowering effect of exercise is commonly assumed, but, in contrast to multi-modal lifestyle interventions, the particular effect of exercise on lipid profiles is less-wellestablished. Methods: Systematic literature search for epidemiological and randomized trials, reviews and meta-analyses evaluating the particular effects of high fitness or exercise interventions on changes in lipid levels. Results: A higher fitness assessed by exercise testing is moderately associated with favourable HDL-cholesterol and triglyceride, but not LDL levels. This is confirmed by findings from randomized trials and meta-analyses, but effects are not consistently observed. Moderate aerobic exercise is preferred over resistance or high-intensity interval exercise. Besides absolute lipid values, exercise favourably influences atherogenic lipid subfractions. The combination of statins with exercise improves clinical outcomes; thus, statins should not be withheld if indicated according to guidelines.Discussion: The effect of exercise on lipid levels is at best moderate, with small improvements in HDL and triglyceride, but not LDL levels. Nonetheless, dyslipidaemia is rarely observed as a single risk factor, and exercise remains a cornerstone of multimodal lifestyle interventions to favourably modify cardiovascular risk.KEY WORDS: Fitness, Exercise, Dyslipidaemia, LDL, StatinsPressler ADynamic Media Sales VerlagarticleSports medicineRC1200-1245DEENDeutsche Zeitschrift für Sportmedizin, Vol 68, Iss 11 (2017) |
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Sports medicine RC1200-1245 Pressler A Sportmedizin im Wandel |
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Problem: Dyslipidaemia and physical inactivity are leading risk factors for the development of atherosclerotic disease, accounting annually for approximately 5.8 million deaths worldwide. A lipid-lowering effect of exercise is commonly assumed, but, in contrast to multi-modal lifestyle interventions, the particular effect of exercise on lipid profiles is less-wellestablished. Methods: Systematic literature search for epidemiological and randomized trials, reviews and meta-analyses evaluating the particular effects of high fitness or exercise interventions on changes in lipid levels. Results: A higher fitness assessed by exercise testing is moderately associated with favourable HDL-cholesterol and triglyceride, but not LDL levels. This is confirmed by findings from randomized trials and meta-analyses, but effects are not consistently observed. Moderate aerobic exercise is preferred over resistance or high-intensity interval exercise. Besides absolute lipid values, exercise favourably influences atherogenic lipid subfractions. The combination of statins with exercise improves clinical outcomes; thus, statins should not be withheld if indicated according to guidelines.Discussion: The effect of exercise on lipid levels is at best moderate, with small improvements in HDL and triglyceride, but not LDL levels. Nonetheless, dyslipidaemia is rarely observed as a single risk factor, and exercise remains a cornerstone of multimodal lifestyle interventions to favourably modify cardiovascular risk.KEY WORDS: Fitness, Exercise, Dyslipidaemia, LDL, Statins |
format |
article |
author |
Pressler A |
author_facet |
Pressler A |
author_sort |
Pressler A |
title |
Sportmedizin im Wandel |
title_short |
Sportmedizin im Wandel |
title_full |
Sportmedizin im Wandel |
title_fullStr |
Sportmedizin im Wandel |
title_full_unstemmed |
Sportmedizin im Wandel |
title_sort |
sportmedizin im wandel |
publisher |
Dynamic Media Sales Verlag |
publishDate |
2017 |
url |
https://doaj.org/article/308553696cda4ae09b1a1e142dc7ade5 |
work_keys_str_mv |
AT presslera sportmedizinimwandel |
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1718426165395324928 |