Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes

The histone folding protein Dpb4 forms histone-like dimers within the ISW2 complex and the Pol ε complex in S. cerevisiae. Here the authors reveal insights into two distinct functions that Dpb4 exerts at DSBs depending on its interactors.

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Autores principales:	Erika Casari, Elisa Gobbini, Marco Gnugnoli, Marco Mangiagalli, Michela Clerici, Maria Pia Longhese
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/308e440c9f65443c829e70f044d62f42
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spelling	oai:doaj.org-article:308e440c9f65443c829e70f044d62f422021-12-02T17:06:12ZDpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes10.1038/s41467-021-25090-92041-1723https://doaj.org/article/308e440c9f65443c829e70f044d62f422021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25090-9https://doaj.org/toc/2041-1723The histone folding protein Dpb4 forms histone-like dimers within the ISW2 complex and the Pol ε complex in S. cerevisiae. Here the authors reveal insights into two distinct functions that Dpb4 exerts at DSBs depending on its interactors.Erika CasariElisa GobbiniMarco GnugnoliMarco MangiagalliMichela ClericiMaria Pia LongheseNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Erika Casari Elisa Gobbini Marco Gnugnoli Marco Mangiagalli Michela Clerici Maria Pia Longhese Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes
description	The histone folding protein Dpb4 forms histone-like dimers within the ISW2 complex and the Pol ε complex in S. cerevisiae. Here the authors reveal insights into two distinct functions that Dpb4 exerts at DSBs depending on its interactors.
format	article
author	Erika Casari Elisa Gobbini Marco Gnugnoli Marco Mangiagalli Michela Clerici Maria Pia Longhese
author_facet	Erika Casari Elisa Gobbini Marco Gnugnoli Marco Mangiagalli Michela Clerici Maria Pia Longhese
author_sort	Erika Casari
title	Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes
title_short	Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes
title_full	Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes
title_fullStr	Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes
title_full_unstemmed	Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes
title_sort	dpb4 promotes resection of dna double-strand breaks and checkpoint activation by acting in two different protein complexes
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/308e440c9f65443c829e70f044d62f42
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Dpb4 promotes resection of DNA double-strand breaks and checkpoint activation by acting in two different protein complexes

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