Antidiabetic screening of some Indonesian marine cyanobacteria collection

Priatni S, Budiwati TA, Ratnaningrum D, Kosasih W, Andryani R, Susanti H, Susilaningsih D. 2016. Antidiabetic screening of some Indonesian marine cyanobacteria collection. Biodiversitas 17: 642-646. Cyanobacteria have been known as a potential extracellular-polysaccharide (EPS) producer. The objecti...

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Autores principales: SRI PRIATNI, THELMA A. BUDIWATI, DIAH RATNANINGRUM, WAWAN KOSASIH, RINA ANDRYANI, HANI SUSANTI, DWI SUSILANINGSIH
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Publicado: MBI & UNS Solo 2016
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spelling oai:doaj.org-article:3093e0b6a1ef4508ac994eb026e8bc5a2021-11-14T02:27:09ZAntidiabetic screening of some Indonesian marine cyanobacteria collection1412-033X2085-472210.13057/biodiv/d170236https://doaj.org/article/3093e0b6a1ef4508ac994eb026e8bc5a2016-08-01T00:00:00Zhttps://smujo.id/biodiv/article/view/339https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Priatni S, Budiwati TA, Ratnaningrum D, Kosasih W, Andryani R, Susanti H, Susilaningsih D. 2016. Antidiabetic screening of some Indonesian marine cyanobacteria collection. Biodiversitas 17: 642-646. Cyanobacteria have been known as a potential extracellular-polysaccharide (EPS) producer. The objective of this study was to screen the marine cyanobacteria as potential antidiabetic agents. The present investigation was designed to determine the antidiabetic activity of EPS, intracellular-polysaccharide (IPS) and biomass extracts from marine cyanobacteria isolates. 10 cyanobacteria isolates were cultivated in IMK medium, at 25oC for 21 days. The morphology of cells was identified by a light microscope. EPS and IPS were separated by ethanol precipitation method and their antidiabetic activity was analyzed by the inhibition of α-glucosidase activity method. Results of morphology identification of 10 cyanobacteria isolates consist of Oscillatoria limnetica, Oscillatoria sp., Leptolyngbya sp., Pseudanabaena sp., Lyngbya sp. and Phormidium sp., Coelastrella sp., Aphanothece sp. and Synechococcus sp., and Chroococcus sp. Almost all of EPS from marine cyanobacteria isolates were potential as inhibitor of α-glucosidase, except for Oscillatoria limnetica and Phormidium sp. isolates. The highest activity in α-glucosidase inhibition was detected in Pseudanabaena sp. (14.02%) and Chroococcus sp. (13.0%) isolates.SRI PRIATNITHELMA A. BUDIWATIDIAH RATNANINGRUMWAWAN KOSASIHRINA ANDRYANIHANI SUSANTIDWI SUSILANINGSIHMBI & UNS Soloarticleantidiabetic, cyanobacteria, extracellular-polysaccharide, screeningBiology (General)QH301-705.5ENBiodiversitas, Vol 17, Iss 2 (2016)
institution DOAJ
collection DOAJ
language EN
topic antidiabetic, cyanobacteria, extracellular-polysaccharide, screening
Biology (General)
QH301-705.5
spellingShingle antidiabetic, cyanobacteria, extracellular-polysaccharide, screening
Biology (General)
QH301-705.5
SRI PRIATNI
THELMA A. BUDIWATI
DIAH RATNANINGRUM
WAWAN KOSASIH
RINA ANDRYANI
HANI SUSANTI
DWI SUSILANINGSIH
Antidiabetic screening of some Indonesian marine cyanobacteria collection
description Priatni S, Budiwati TA, Ratnaningrum D, Kosasih W, Andryani R, Susanti H, Susilaningsih D. 2016. Antidiabetic screening of some Indonesian marine cyanobacteria collection. Biodiversitas 17: 642-646. Cyanobacteria have been known as a potential extracellular-polysaccharide (EPS) producer. The objective of this study was to screen the marine cyanobacteria as potential antidiabetic agents. The present investigation was designed to determine the antidiabetic activity of EPS, intracellular-polysaccharide (IPS) and biomass extracts from marine cyanobacteria isolates. 10 cyanobacteria isolates were cultivated in IMK medium, at 25oC for 21 days. The morphology of cells was identified by a light microscope. EPS and IPS were separated by ethanol precipitation method and their antidiabetic activity was analyzed by the inhibition of α-glucosidase activity method. Results of morphology identification of 10 cyanobacteria isolates consist of Oscillatoria limnetica, Oscillatoria sp., Leptolyngbya sp., Pseudanabaena sp., Lyngbya sp. and Phormidium sp., Coelastrella sp., Aphanothece sp. and Synechococcus sp., and Chroococcus sp. Almost all of EPS from marine cyanobacteria isolates were potential as inhibitor of α-glucosidase, except for Oscillatoria limnetica and Phormidium sp. isolates. The highest activity in α-glucosidase inhibition was detected in Pseudanabaena sp. (14.02%) and Chroococcus sp. (13.0%) isolates.
format article
author SRI PRIATNI
THELMA A. BUDIWATI
DIAH RATNANINGRUM
WAWAN KOSASIH
RINA ANDRYANI
HANI SUSANTI
DWI SUSILANINGSIH
author_facet SRI PRIATNI
THELMA A. BUDIWATI
DIAH RATNANINGRUM
WAWAN KOSASIH
RINA ANDRYANI
HANI SUSANTI
DWI SUSILANINGSIH
author_sort SRI PRIATNI
title Antidiabetic screening of some Indonesian marine cyanobacteria collection
title_short Antidiabetic screening of some Indonesian marine cyanobacteria collection
title_full Antidiabetic screening of some Indonesian marine cyanobacteria collection
title_fullStr Antidiabetic screening of some Indonesian marine cyanobacteria collection
title_full_unstemmed Antidiabetic screening of some Indonesian marine cyanobacteria collection
title_sort antidiabetic screening of some indonesian marine cyanobacteria collection
publisher MBI & UNS Solo
publishDate 2016
url https://doaj.org/article/3093e0b6a1ef4508ac994eb026e8bc5a
work_keys_str_mv AT sripriatni antidiabeticscreeningofsomeindonesianmarinecyanobacteriacollection
AT thelmaabudiwati antidiabeticscreeningofsomeindonesianmarinecyanobacteriacollection
AT diahratnaningrum antidiabeticscreeningofsomeindonesianmarinecyanobacteriacollection
AT wawankosasih antidiabeticscreeningofsomeindonesianmarinecyanobacteriacollection
AT rinaandryani antidiabeticscreeningofsomeindonesianmarinecyanobacteriacollection
AT hanisusanti antidiabeticscreeningofsomeindonesianmarinecyanobacteriacollection
AT dwisusilaningsih antidiabeticscreeningofsomeindonesianmarinecyanobacteriacollection
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