Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator

Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator

Yamada, Motoike, Kojima et al. undertake a GWAS study on 19,722 participants from two Japanese populations for lung function with adjustment for fractional exhaled nitric oxide levels to account for airway inflammation. The authors identify variants of the RNF5/AGER locus and explore their three-dim...

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Autores principales: Mitsuhiro Yamada, Ikuko N. Motoike, Kaname Kojima, Nobuo Fuse, Atsushi Hozawa, Shinichi Kuriyama, Fumiki Katsuoka, Shu Tadaka, Matsuyuki Shirota, Miyuki Sakurai, Tomohiro Nakamura, Yohei Hamanaka, Kichiya Suzuki, Junichi Sugawara, Soichi Ogishima, Akira Uruno, Eiichi N. Kodama, Naoya Fujino, Tadahisa Numakura, Tomohiro Ichikawa, Ayumi Mitsune, Takashi Ohe, Kengo Kinoshita, Masakazu Ichinose, Hisatoshi Sugiura, Masayuki Yamamoto
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/309a84e839cb4d95a792a8865914587f
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spelling oai:doaj.org-article:309a84e839cb4d95a792a8865914587f2021-11-21T12:08:17ZGenetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator10.1038/s42003-021-02813-82399-3642https://doaj.org/article/309a84e839cb4d95a792a8865914587f2021-11-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02813-8https://doaj.org/toc/2399-3642Yamada, Motoike, Kojima et al. undertake a GWAS study on 19,722 participants from two Japanese populations for lung function with adjustment for fractional exhaled nitric oxide levels to account for airway inflammation. The authors identify variants of the RNF5/AGER locus and explore their three-dimensional protein interactions to better investigate the association between these variants and lung function.Mitsuhiro YamadaIkuko N. MotoikeKaname KojimaNobuo FuseAtsushi HozawaShinichi KuriyamaFumiki KatsuokaShu TadakaMatsuyuki ShirotaMiyuki SakuraiTomohiro NakamuraYohei HamanakaKichiya SuzukiJunichi SugawaraSoichi OgishimaAkira UrunoEiichi N. KodamaNaoya FujinoTadahisa NumakuraTomohiro IchikawaAyumi MitsuneTakashi OheKengo KinoshitaMasakazu IchinoseHisatoshi SugiuraMasayuki YamamotoNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Mitsuhiro Yamada
Ikuko N. Motoike
Kaname Kojima
Nobuo Fuse
Atsushi Hozawa
Shinichi Kuriyama
Fumiki Katsuoka
Shu Tadaka
Matsuyuki Shirota
Miyuki Sakurai
Tomohiro Nakamura
Yohei Hamanaka
Kichiya Suzuki
Junichi Sugawara
Soichi Ogishima
Akira Uruno
Eiichi N. Kodama
Naoya Fujino
Tadahisa Numakura
Tomohiro Ichikawa
Ayumi Mitsune
Takashi Ohe
Kengo Kinoshita
Masakazu Ichinose
Hisatoshi Sugiura
Masayuki Yamamoto
Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator
description Yamada, Motoike, Kojima et al. undertake a GWAS study on 19,722 participants from two Japanese populations for lung function with adjustment for fractional exhaled nitric oxide levels to account for airway inflammation. The authors identify variants of the RNF5/AGER locus and explore their three-dimensional protein interactions to better investigate the association between these variants and lung function.
format article
author Mitsuhiro Yamada
Ikuko N. Motoike
Kaname Kojima
Nobuo Fuse
Atsushi Hozawa
Shinichi Kuriyama
Fumiki Katsuoka
Shu Tadaka
Matsuyuki Shirota
Miyuki Sakurai
Tomohiro Nakamura
Yohei Hamanaka
Kichiya Suzuki
Junichi Sugawara
Soichi Ogishima
Akira Uruno
Eiichi N. Kodama
Naoya Fujino
Tadahisa Numakura
Tomohiro Ichikawa
Ayumi Mitsune
Takashi Ohe
Kengo Kinoshita
Masakazu Ichinose
Hisatoshi Sugiura
Masayuki Yamamoto
author_facet Mitsuhiro Yamada
Ikuko N. Motoike
Kaname Kojima
Nobuo Fuse
Atsushi Hozawa
Shinichi Kuriyama
Fumiki Katsuoka
Shu Tadaka
Matsuyuki Shirota
Miyuki Sakurai
Tomohiro Nakamura
Yohei Hamanaka
Kichiya Suzuki
Junichi Sugawara
Soichi Ogishima
Akira Uruno
Eiichi N. Kodama
Naoya Fujino
Tadahisa Numakura
Tomohiro Ichikawa
Ayumi Mitsune
Takashi Ohe
Kengo Kinoshita
Masakazu Ichinose
Hisatoshi Sugiura
Masayuki Yamamoto
author_sort Mitsuhiro Yamada
title Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator
title_short Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator
title_full Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator
title_fullStr Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator
title_full_unstemmed Genetic loci for lung function in Japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator
title_sort genetic loci for lung function in japanese adults with adjustment for exhaled nitric oxide levels as airway inflammation indicator
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/309a84e839cb4d95a792a8865914587f
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