Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1

Holliday junctions (HJs) are DNA intermediates in genetic recombination that are resolved by nuclease, termed resolvase, to ensure genome stability. Here, the authors provide insights into the resolution process by resolving the crystal structure of the chloroplast resolvase MOC1 with HJs substrates...

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Autores principales: Junjie Yan, Sixing Hong, Zeyuan Guan, Wenjing He, Delin Zhang, Ping Yin
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/309b32092ec74389b32c6020f082a4e2
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spelling oai:doaj.org-article:309b32092ec74389b32c6020f082a4e22021-12-02T16:49:14ZStructural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC110.1038/s41467-020-15242-82041-1723https://doaj.org/article/309b32092ec74389b32c6020f082a4e22020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15242-8https://doaj.org/toc/2041-1723Holliday junctions (HJs) are DNA intermediates in genetic recombination that are resolved by nuclease, termed resolvase, to ensure genome stability. Here, the authors provide insights into the resolution process by resolving the crystal structure of the chloroplast resolvase MOC1 with HJs substrates.Junjie YanSixing HongZeyuan GuanWenjing HeDelin ZhangPing YinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Junjie Yan
Sixing Hong
Zeyuan Guan
Wenjing He
Delin Zhang
Ping Yin
Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1
description Holliday junctions (HJs) are DNA intermediates in genetic recombination that are resolved by nuclease, termed resolvase, to ensure genome stability. Here, the authors provide insights into the resolution process by resolving the crystal structure of the chloroplast resolvase MOC1 with HJs substrates.
format article
author Junjie Yan
Sixing Hong
Zeyuan Guan
Wenjing He
Delin Zhang
Ping Yin
author_facet Junjie Yan
Sixing Hong
Zeyuan Guan
Wenjing He
Delin Zhang
Ping Yin
author_sort Junjie Yan
title Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1
title_short Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1
title_full Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1
title_fullStr Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1
title_full_unstemmed Structural insights into sequence-dependent Holliday junction resolution by the chloroplast resolvase MOC1
title_sort structural insights into sequence-dependent holliday junction resolution by the chloroplast resolvase moc1
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/309b32092ec74389b32c6020f082a4e2
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AT sixinghong structuralinsightsintosequencedependenthollidayjunctionresolutionbythechloroplastresolvasemoc1
AT zeyuanguan structuralinsightsintosequencedependenthollidayjunctionresolutionbythechloroplastresolvasemoc1
AT wenjinghe structuralinsightsintosequencedependenthollidayjunctionresolutionbythechloroplastresolvasemoc1
AT delinzhang structuralinsightsintosequencedependenthollidayjunctionresolutionbythechloroplastresolvasemoc1
AT pingyin structuralinsightsintosequencedependenthollidayjunctionresolutionbythechloroplastresolvasemoc1
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