Exploiting mitochondrial dysfunction for effective elimination of imatinib-resistant leukemic cells.

Exploiting mitochondrial dysfunction for effective elimination of imatinib-resistant leukemic cells.

Challenges today concern chronic myeloid leukemia (CML) patients resistant to imatinib. There is growing evidence that imatinib-resistant leukemic cells present abnormal glucose metabolism but the impact on mitochondria has been neglected. Our work aimed to better understand and exploit the metaboli...

Full description

Saved in:
Bibliographic Details
Main Authors: Jérome Kluza, Manel Jendoubi, Caroline Ballot, Abir Dammak, Aurélie Jonneaux, Thierry Idziorek, Sami Joha, Véronique Dauphin, Myriam Malet-Martino, Stéphane Balayssac, Patrice Maboudou, Gilbert Briand, Pierre Formstecher, Bruno Quesnel, Philippe Marchetti
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/30a12df69d4f470da9eece553ed01f44
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/30a12df69d4f470da9eece553ed01f44

Similar Items