Development of an Opsonophagocytic Killing Assay Using HL-60 Cells for Detection of Functional Antibodies against <italic toggle="yes">Streptococcus pyogenes</italic>
ABSTRACT The clinical development of group A streptococcal (GAS) vaccines will require the implementation of a standardized, high-throughput assay to measure the activity of functional opsonic antibodies in vaccine recipients. In the present study, we adapted and modified the HL-60-based protocol th...
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Main Authors: | , , , |
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Format: | article |
Language: | EN |
Published: |
American Society for Microbiology
2018
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Online Access: | https://doaj.org/article/30a94378ff9a4a768bff82461ec567d5 |
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