LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate

Pioneer transcription factors access their DNA binding motifs in closed chromatin and often act in cell fate reprogramming. Here, Jin et al. present biochemical evidence for a pioneer factor in plants and show that LFY promotes floral cell fate and locally unlocks chromatin by displacing histone H1...

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Autores principales: Run Jin, Samantha Klasfeld, Yang Zhu, Meilin Fernandez Garcia, Jun Xiao, Soon-Ki Han, Adam Konkol, Doris Wagner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/30ac2aa2b2134476b24948b7bf252727
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spelling oai:doaj.org-article:30ac2aa2b2134476b24948b7bf2527272021-12-02T10:47:59ZLEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate10.1038/s41467-020-20883-w2041-1723https://doaj.org/article/30ac2aa2b2134476b24948b7bf2527272021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20883-whttps://doaj.org/toc/2041-1723Pioneer transcription factors access their DNA binding motifs in closed chromatin and often act in cell fate reprogramming. Here, Jin et al. present biochemical evidence for a pioneer factor in plants and show that LFY promotes floral cell fate and locally unlocks chromatin by displacing histone H1 and recruiting SWI/SNF chromatin remodelers.Run JinSamantha KlasfeldYang ZhuMeilin Fernandez GarciaJun XiaoSoon-Ki HanAdam KonkolDoris WagnerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Run Jin
Samantha Klasfeld
Yang Zhu
Meilin Fernandez Garcia
Jun Xiao
Soon-Ki Han
Adam Konkol
Doris Wagner
LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
description Pioneer transcription factors access their DNA binding motifs in closed chromatin and often act in cell fate reprogramming. Here, Jin et al. present biochemical evidence for a pioneer factor in plants and show that LFY promotes floral cell fate and locally unlocks chromatin by displacing histone H1 and recruiting SWI/SNF chromatin remodelers.
format article
author Run Jin
Samantha Klasfeld
Yang Zhu
Meilin Fernandez Garcia
Jun Xiao
Soon-Ki Han
Adam Konkol
Doris Wagner
author_facet Run Jin
Samantha Klasfeld
Yang Zhu
Meilin Fernandez Garcia
Jun Xiao
Soon-Ki Han
Adam Konkol
Doris Wagner
author_sort Run Jin
title LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
title_short LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
title_full LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
title_fullStr LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
title_full_unstemmed LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
title_sort leafy is a pioneer transcription factor and licenses cell reprogramming to floral fate
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/30ac2aa2b2134476b24948b7bf252727
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