LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate
Pioneer transcription factors access their DNA binding motifs in closed chromatin and often act in cell fate reprogramming. Here, Jin et al. present biochemical evidence for a pioneer factor in plants and show that LFY promotes floral cell fate and locally unlocks chromatin by displacing histone H1...
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Nature Portfolio
2021
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oai:doaj.org-article:30ac2aa2b2134476b24948b7bf2527272021-12-02T10:47:59ZLEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate10.1038/s41467-020-20883-w2041-1723https://doaj.org/article/30ac2aa2b2134476b24948b7bf2527272021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20883-whttps://doaj.org/toc/2041-1723Pioneer transcription factors access their DNA binding motifs in closed chromatin and often act in cell fate reprogramming. Here, Jin et al. present biochemical evidence for a pioneer factor in plants and show that LFY promotes floral cell fate and locally unlocks chromatin by displacing histone H1 and recruiting SWI/SNF chromatin remodelers.Run JinSamantha KlasfeldYang ZhuMeilin Fernandez GarciaJun XiaoSoon-Ki HanAdam KonkolDoris WagnerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021) |
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Science Q Run Jin Samantha Klasfeld Yang Zhu Meilin Fernandez Garcia Jun Xiao Soon-Ki Han Adam Konkol Doris Wagner LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate |
description |
Pioneer transcription factors access their DNA binding motifs in closed chromatin and often act in cell fate reprogramming. Here, Jin et al. present biochemical evidence for a pioneer factor in plants and show that LFY promotes floral cell fate and locally unlocks chromatin by displacing histone H1 and recruiting SWI/SNF chromatin remodelers. |
format |
article |
author |
Run Jin Samantha Klasfeld Yang Zhu Meilin Fernandez Garcia Jun Xiao Soon-Ki Han Adam Konkol Doris Wagner |
author_facet |
Run Jin Samantha Klasfeld Yang Zhu Meilin Fernandez Garcia Jun Xiao Soon-Ki Han Adam Konkol Doris Wagner |
author_sort |
Run Jin |
title |
LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate |
title_short |
LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate |
title_full |
LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate |
title_fullStr |
LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate |
title_full_unstemmed |
LEAFY is a pioneer transcription factor and licenses cell reprogramming to floral fate |
title_sort |
leafy is a pioneer transcription factor and licenses cell reprogramming to floral fate |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/30ac2aa2b2134476b24948b7bf252727 |
work_keys_str_mv |
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1718396700688646144 |