Simple ruthenium-catalyzed reductive amination enables the synthesis of a broad range of primary amines

Synthesis of primary amines via operationally simple, inexpensive and environmentally friendly methodologies has high impact in industrial settings. Here, the authors show a reductive amination process involving a ruthenium catalyst, aldehydes/ketones, ammonia, and hydrogen that displays a remarkabl...

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Auteurs principaux: Thirusangumurugan Senthamarai, Kathiravan Murugesan, Jacob Schneidewind, Narayana V. Kalevaru, Wolfgang Baumann, Helfried Neumann, Paul C. J. Kamer, Matthias Beller, Rajenahally V. Jagadeesh
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/30b3c5ca124944a5a205b7b7aa5dfedb
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Résumé:Synthesis of primary amines via operationally simple, inexpensive and environmentally friendly methodologies has high impact in industrial settings. Here, the authors show a reductive amination process involving a ruthenium catalyst, aldehydes/ketones, ammonia, and hydrogen that displays a remarkable scope of primary amine products.