Simple ruthenium-catalyzed reductive amination enables the synthesis of a broad range of primary amines

Synthesis of primary amines via operationally simple, inexpensive and environmentally friendly methodologies has high impact in industrial settings. Here, the authors show a reductive amination process involving a ruthenium catalyst, aldehydes/ketones, ammonia, and hydrogen that displays a remarkabl...

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Autores principales: Thirusangumurugan Senthamarai, Kathiravan Murugesan, Jacob Schneidewind, Narayana V. Kalevaru, Wolfgang Baumann, Helfried Neumann, Paul C. J. Kamer, Matthias Beller, Rajenahally V. Jagadeesh
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/30b3c5ca124944a5a205b7b7aa5dfedb
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spelling oai:doaj.org-article:30b3c5ca124944a5a205b7b7aa5dfedb2021-12-02T15:33:58ZSimple ruthenium-catalyzed reductive amination enables the synthesis of a broad range of primary amines10.1038/s41467-018-06416-62041-1723https://doaj.org/article/30b3c5ca124944a5a205b7b7aa5dfedb2018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06416-6https://doaj.org/toc/2041-1723Synthesis of primary amines via operationally simple, inexpensive and environmentally friendly methodologies has high impact in industrial settings. Here, the authors show a reductive amination process involving a ruthenium catalyst, aldehydes/ketones, ammonia, and hydrogen that displays a remarkable scope of primary amine products.Thirusangumurugan SenthamaraiKathiravan MurugesanJacob SchneidewindNarayana V. KalevaruWolfgang BaumannHelfried NeumannPaul C. J. KamerMatthias BellerRajenahally V. JagadeeshNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Thirusangumurugan Senthamarai
Kathiravan Murugesan
Jacob Schneidewind
Narayana V. Kalevaru
Wolfgang Baumann
Helfried Neumann
Paul C. J. Kamer
Matthias Beller
Rajenahally V. Jagadeesh
Simple ruthenium-catalyzed reductive amination enables the synthesis of a broad range of primary amines
description Synthesis of primary amines via operationally simple, inexpensive and environmentally friendly methodologies has high impact in industrial settings. Here, the authors show a reductive amination process involving a ruthenium catalyst, aldehydes/ketones, ammonia, and hydrogen that displays a remarkable scope of primary amine products.
format article
author Thirusangumurugan Senthamarai
Kathiravan Murugesan
Jacob Schneidewind
Narayana V. Kalevaru
Wolfgang Baumann
Helfried Neumann
Paul C. J. Kamer
Matthias Beller
Rajenahally V. Jagadeesh
author_facet Thirusangumurugan Senthamarai
Kathiravan Murugesan
Jacob Schneidewind
Narayana V. Kalevaru
Wolfgang Baumann
Helfried Neumann
Paul C. J. Kamer
Matthias Beller
Rajenahally V. Jagadeesh
author_sort Thirusangumurugan Senthamarai
title Simple ruthenium-catalyzed reductive amination enables the synthesis of a broad range of primary amines
title_short Simple ruthenium-catalyzed reductive amination enables the synthesis of a broad range of primary amines
title_full Simple ruthenium-catalyzed reductive amination enables the synthesis of a broad range of primary amines
title_fullStr Simple ruthenium-catalyzed reductive amination enables the synthesis of a broad range of primary amines
title_full_unstemmed Simple ruthenium-catalyzed reductive amination enables the synthesis of a broad range of primary amines
title_sort simple ruthenium-catalyzed reductive amination enables the synthesis of a broad range of primary amines
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/30b3c5ca124944a5a205b7b7aa5dfedb
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